2'-Methyl-pyrazolo[4',3':16,17]androst-5-en-3β-ol.

Acta Crystallogr Sect E Struct Rep Online

Department of Medicinal Chemistry, School of Pharmacy, Fudan University, 138 Yixueyuan Road Shanghai 200032, People's Republic of China.

Published: May 2009

In the title compound, C(21)H(30)N(2)O, there are five fused rings. The A and C rings adopt chair conformations, ring B adopts an 8β,9α-half-chair conformation and ring D adopts a 14α-envelope conformation. The pyrazole ring is planar. Inter-molecular O-H⋯N hydrogen bonds [H⋯N = 1.88 (5) Å] help to stabilize the crystal structure. The absolute structure was deduced from those of the starting materials.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2969823PMC
http://dx.doi.org/10.1107/S1600536809019539DOI Listing

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