In the title compound, C(21)H(30)N(2)O, there are five fused rings. The A and C rings adopt chair conformations, ring B adopts an 8β,9α-half-chair conformation and ring D adopts a 14α-envelope conformation. The pyrazole ring is planar. Inter-molecular O-H⋯N hydrogen bonds [H⋯N = 1.88 (5) Å] help to stabilize the crystal structure. The absolute structure was deduced from those of the starting materials.
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http://dx.doi.org/10.1107/S1600536809019539 | DOI Listing |
Ultrasonics
March 2025
School of Information Science and Technology, ShanghaiTech University, Shanghai, 201210, China; Shanghai Engineering Research Center of Intelligent Vision and Imaging, ShanghaiTech University, Shanghai, 201210, China; Key Laboratory of Biomedical Imaging Science and System, Chinese Academy of Sciences, Shenzhen, 518055, China. Electronic address:
Bent-ray tracing ultrasound computed tomography (USCT) is a promising technique for breast cancer screening which quantitatively provides speed-of-sound (SOS) distribution in human breasts. In this modality, SOS images are reconstructed with an iterative process to match the measured time-of-flights and the ones predicted by Eikonal equation solved with the fast marching method (FMM). The Eikonal equation is meant to be applied in SOS heterogeneous media and its evaluation with FMM is an computational expensive process.
View Article and Find Full Text PDFActa Crystallogr C Struct Chem
April 2025
Laboratory of Bioorganic Chemistry and Chemical Biology, Center for Nanotechnology, Heisenbergstrasse 11, 48149 Münster, Germany.
Isoguanine nucleosides constructed by different heterocyclic skeletons play a significant role in the context of genetic code expansion, as well as for purine-purine base pairing. However, with respect to structure analysis, only limited information is available on this class of nucleosides. In this study, the single-crystal X-ray structure of 8-ethynyl-2'-deoxyisoguanosine, CHNO·CHNO·2HO (1), has been investigated.
View Article and Find Full Text PDFActa Crystallogr E Crystallogr Commun
March 2025
School of Science and Technology, Nottingham Trent University, Nottingham NG11, 8NS, United Kingdom.
Diphenidine (), a dissociative anaesthetic, was first reported in 2013. Since then, a number of derivatives 2-methoxphenidine () have been produced by clandestine laboratories and sold as . Fluorinated diphenidines, namely, [1-(2,6-di-fluoro-phen-yl)-2-phenyl-eth-yl]di-methyl-aza-nium chloride, CHFN·Cl, (), [1-(2,6-di-fluoro-phen-yl)-2-phenyl-eth-yl](eth-yl)aza-nium chloride di-chloro-methane hemisolvate, 2CHFN·2Cl·CHCl, (), -but-yl[1-(2,6-di-fluoro-phen-yl)-2-phenyl-eth-yl]aza-nium chloride, CHFN·Cl, (), 1-[1-(2,6-di-fluoro-phen-yl)-2-phenyl-eth-yl]pyrrolidin-1-ium chloride, CHFN·Cl, (), and 1-[1-(2,3,4,5,6-penta-fluoro-phen-yl)-2-phenyl-eth-yl]piperidin-1-ium chloride, CHFN·Cl, (), were synthesized and structurally characterized by H, C and F NMR spectroscopy, and single-crystal X-ray diffraction.
View Article and Find Full Text PDFActa Crystallogr E Crystallogr Commun
March 2025
Department of PG Studies and Research in Physics Albert Einstein Block UCS Tumkur University, Tumkur Karnataka-572103 India.
The title compound, CHNO, was synthesized by S2 reaction of bromo-methyl coumarin with 4,4-di-methyl-piperidine-2,6-dione. The mol-ecule crystalizes in the monoclinic system with space group 2/. The coumarin unit is almost planar with a dihedral angle between the aromatic rings of 0.
View Article and Find Full Text PDFActa Crystallogr E Crystallogr Commun
March 2025
Program in Chemistry Faculty of Science and Technology Rajabhat Rajanagarindra University,Chachoengsao 24000 Thailand.
5,10-Dihy-droxy-9-meth-oxy-2,2-dimethyl-12-(2-methyl-but-3-en-2-yl)-2,6-pyrano[3,2-]xanthen-6-one, CHO (), is a prenylated xanthone that was synthesized from 5,9,10-trihy-droxy-2,2-dimethyl-12-(2-methyl-but-3-en-2-yl)-2,6-pyrano[3,2-]xanthen-6-one or macluraxanthone (), a known compound isolated from Pierre. The present study describes the synthesis of compound by methyl-ation reaction of , and its crystallographic characterization. Compound 2 features a planar xanthone core and a bent pyrano ring adopting a half-boat conformation.
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