The title compound, C(19)H(12)Br(3)N, was synthesized by N-alkyl-ation of 1-bromo-4-(bromo-meth-yl)benzene with 3,6-dibromo-9H-carbazole. There are two unique mol-ecules in the asymmetric unit. The carbazole ring system is essentially planar, with a mean deviation of 0.0402 Å for one mol-ecule and 0.0279 Å for the other. The carbazole planes are inclined to the benzene ring planes at dihedral angles of 58.3 (3) and 71.1 (3)° in the two mol-ecules.
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http://dx.doi.org/10.1107/S1600536808042827 | DOI Listing |
J Med Internet Res
January 2025
College of Nursing Science, Kyung Hee University, Seoul, Republic of Korea.
Background: Emerging infectious disease disasters receive extensive media coverage and public attention. Nurse burnout and attrition peak during health crises such as pandemics. However, there is limited research on nursing issues related to repeated emerging infectious disease crises over time.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Department of Health Economics and Health Services Research, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
Systematic reviews (SR) synthesize evidence-based medical literature, but they involve labor-intensive manual article screening. Large language models (LLMs) can select relevant literature, but their quality and efficacy are still being determined compared to humans. We evaluated the overlap between title- and abstract-based selected articles of 18 different LLMs and human-selected articles for three SR.
View Article and Find Full Text PDFJ Clin Gastroenterol
January 2025
Department of Gastroenterology, Changhai Clinical Research Unit, Changhai Hospital.
Aims: ERCP training should adapt to the rapid development of ERCP technology and indications. China has a large population and vast land area, but ERCP training resources are insufficient. To make effective use of scarce ERCP training resources, the Standardized Training for ERCP Procedure (STEP) program was launched as a pilot trial.
View Article and Find Full Text PDFCurr Pain Headache Rep
January 2025
Department of Anesthesiology, Perioperative, and Pain Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
Purpose Of Review: Knee osteoarthritis (OA) is a gradual deterioration of articular cartilage characterized by pain and physical dysfunction. Although analgesic pharmacological agents are the first-line treatment for knee OA, they are not effective for all patients. In this study, we evaluate the efficacy of an intra-articular injection treatment using platelet-rich plasma (PRP) in reducing pain and improving functional ability.
View Article and Find Full Text PDFJ Robot Surg
January 2025
Sengupta Urology, Glen Waverley, Vic, Australia.
This study compares laparoscopic (LRP) and robotic-assisted (RARP) radical prostatectomy to identify external and internal disruptive events, focusing on tasks that require heightened attention and coordination among the surgical team. Observations conducted across three hospitals in Australia and China. Data collection was rigorously ensured through the analysis of video recordings and consultations with surgeons, followed by statistical analysis using the Wilcoxon Signed Rank test.
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