(Z)-5-Fluoro-3-[(1H-pyrrol-2-yl)methyl-ene]indolin-2-one.

Acta Crystallogr Sect E Struct Rep Online

Department of Chemistry, Southern Methodist University, Dallas, TX 75275, USA.

Published: December 2008

The title compound, C(13)H(9)FN(2)O, a potential neuroprotective agent, consists of an indolinone and a pyrrolyl unit [dihedral angle between the ring planes = 4.9 (1)°]. An intra-molecular hydrogen bond between the carbonyl O atom and the NH group of pyrrole correlates with the Z arrangement of the substituents at the C=C bond. In the crystal, inversion dimers occur, linked by pairs of N-H⋯O bonds.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967860PMC
http://dx.doi.org/10.1107/S1600536808040178DOI Listing

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(Z)-5-Fluoro-3-[(1H-pyrrol-2-yl)methyl-ene]indolin-2-one.

Acta Crystallogr Sect E Struct Rep Online

December 2008

Department of Chemistry, Southern Methodist University, Dallas, TX 75275, USA.

The title compound, C(13)H(9)FN(2)O, a potential neuroprotective agent, consists of an indolinone and a pyrrolyl unit [dihedral angle between the ring planes = 4.9 (1)°]. An intra-molecular hydrogen bond between the carbonyl O atom and the NH group of pyrrole correlates with the Z arrangement of the substituents at the C=C bond.

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