In the title compound, C(20)H(15)ClN(4)O(7)S·4CH(3)COOH, the central o-vanillin group makes dihedral angles of 9.50 (11) and 42.86 (7)°, respectively, with its attached pyridine and nitro-benzene rings. The crystal packing is stabilized by N-H⋯O, O-H⋯O and O-H⋯N hydrogen bonds and C-H⋯O inter-actions, leading to an infinite three-dimensional network. A short intramolecular C-H⋯O contact is also seen.
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http://dx.doi.org/10.1107/S1600536808034089 | DOI Listing |
Acta Pol Pharm
August 2012
Department of Pharmaceutical Chemistry, ISF College of Pharmacy, Ferozepur Road, Moga-142001, India.
A series of (E)-N'-(substituted benzylidene)isonicotinohydrazide derivatives were synthesized by coupling isoniazid with differently substituted aldehydes and benzophenones in the presence of absolute ethanol along with catalytic amount of glacial acetic acid. The structure of all the synthesized compounds were confirmed and characterized by using various spectral technique like IR, 1H NMR, 13C NMR and mass spectroscopy. All the synthesized compounds were evaluated for their antimicrobial activity in terms of zone of inhibition, minimum inhibitory concentration, minimum bactericidal concentration and minimum fungicidal concentration in camparison to the standard drugs.
View Article and Find Full Text PDFActa Crystallogr Sect E Struct Rep Online
October 2008
In the title compound, C(20)H(15)ClN(4)O(7)S·4CH(3)COOH, the central o-vanillin group makes dihedral angles of 9.50 (11) and 42.86 (7)°, respectively, with its attached pyridine and nitro-benzene rings.
View Article and Find Full Text PDFActa Crystallogr C
December 2007
College of Sciences, Tianjin University of Science and Technology, Tianjin 300222, People's Republic of China.
In the title compound, C21H18ClN3O5S x C2H4O2, a combination of O-H...
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