The title compound, C(21)H(21)N(3)O(2), was obtained following a five-step synthetic procedure yielding weakly diffracting rod and needle-shaped crystals which crystallized concomitantly. Structural analysis of a rod-shaped crystal showed that the central seven-membered heterocyclic ring adopts a conformation that is perhaps best described as a distorted boat, with the H-bearing (CH(2) and NH) atoms lying well out of the least-squares mean plane fitted through the other five atoms in the ring (r.m.s. deviation 0.075 Å). In the crystal, the compound packs as a twisted chain, which propagates along the b axis by means of an R(1) (2)(6) motif formed by one of the carbonyl O atoms acting as a bifurcated acceptor in an N-H⋯O and C-H⋯O inter-action. No diffraction was observed from the needle-shaped crystals.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983587 | PMC |
| http://dx.doi.org/10.1107/S1600536810005477 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A 77-year-old man was referred to our department because of macrohematuria, oliguria, and a serum creatinine level of 2.47 mg/dL during boron neutron capture therapy (BNCT) for oropharyngeal cancer. At baseline, his creatinine level had been 0.
View Article and Find Full Text PDFPreparation and Thermal Performance Study of a Novel Organic-Inorganic Eutectic Phase Change Material Based on Sodium Acetate Trihydrate and Polyethylene Glycol for Heat Recovery.
Materials (Basel)
January 2025
School of Energy and Automotive Engineering, Shunde Polytechnic, Foshan 528300, China.
A novel organic-inorganic eutectic phase change material (PCM) based on sodium acetate trihydrate (SAT) and polyethylene glycol (PEG) was developed to meet the needs of heat recovery and building heating. Three kinds of PEG with different molecular weights were selected to form organic-inorganic eutectic PCM with SAT. The thermal properties of three series of SAT-PEG eutectic PCM were compared based on DSC results, focusing on the impact of PEG addition on the phase change temperature and enthalpy of SAT, as well as the melting uniformity.
View Article and Find Full Text PDFCharacterization of the sunflower oil-based oleogel developed by the ferulic acid/monoglyceride mixture and its application in chocolate preparation.
Food Chem X
January 2025
School of Food Science, Henan Institute of Science and Technology, Xinxiang 453003, China.
The ferulic acid (FA) / monoglyceride (MG) mixture could act as a gelator to structure sunflower oil at the gelator concentration () ≥ 4 % and the FA/MG ratios () of 0:100, 25:75, 50:50 and 75:25. The rectangular FA and needle-shaped MG crystals in the oleogel interlock with each other to form a 3D network, restricting the flow of oil. The gel strength and rheological performance of the oleogel were positively correlated with and negatively correlated with storage temperature ().
View Article and Find Full Text PDFSynthesis and crystal structure of 1-1,2,4-triazole-3,5-di-amine monohydrate.
Acta Crystallogr E Crystallogr Commun
October 2024
Faculty of Environment and Information Sciences Yokohama National University, 79-7 Tokiwadai Hodogaya-ku Yokohama-shi Kanagawa 240-8501 Japan.
The title compound, a hydrate of 3,5-di-amino-1,2,4-triazole (DATA), CHN·HO, was synthesized in the presence of sodium perchlorate. The evaporation of HO from its aqueous solution resulted in anhydrous DATA, suggesting that sodium perchlorate was required to precipitate the DATA hydrate. The DATA hydrate crystallizes in the 2/ space group in the form of needle-shaped crystals with one DATA and one water mol-ecule in the asymmetric unit.
View Article and Find Full Text PDFGaucher-like crystal-storing histiocytosis associated with kappa chain myeloma: A case report with next generation sequencing study.
Pathol Res Pract
November 2024
Department of Pathology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address:
Article Synopsis
- * The case study illustrates a patient with kappa chain myeloma who exhibited Gaucher-like crystal-storing histiocytosis in bone marrow, identified through various methods including biopsy and next generation sequencing (NGS).
- * Findings indicated the presence of distinct rhomboid crystals and several genetic mutations linked to poorer survival rates in myeloma patients, suggesting that pathologists should consider crystal-storing histiocytosis when identifying such crystals in bone marrow.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!