In the title compound, C(4)HCl(2)NO(3), the essentially planar (maximum deviation = 0.023 Å for the ring O atom) mol-ecules form N-H⋯O hydrogen bonds between mol-ecules lying about inversion centers, forming eight-membered rings with an R(2) (2)(8) motif in graph-set notation.
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http://dx.doi.org/10.1107/S1600536809034606 | DOI Listing |
Anticancer Agents Med Chem
January 2025
Experiment Center for Science and Technology, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Unlabelled: Mesenchymal‒epithelial transition factor (c-Met), a receptortyrosine kinase (RTK), plays a vital role in cell proliferation, migration and invasion, and tumour metastasis.
Objective: With increasing duration of treatment, many tumours gradually develop drug resistance. Therefore, novel antitumour drugs need to be developed to treat patients with tumours.
iScience
January 2025
Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
ETV2/ER71, an ETS (E-twenty six) transcription factor, is critical for hematopoiesis and vascular development. However, research about the molecular mechanisms behind ETV2-mediated gene transcription is limited. Herein, we demonstrate that ETV2 and KDM4A, an H3K9 demethylase, regulate hematopoietic and endothelial genes.
View Article and Find Full Text PDFResusc Plus
January 2025
Emergency Medical Services, Capital Region of Denmark, Ballerup, Denmark.
Unlabelled: Out-of-hospital cardiac arrest (OHCA) remains a critical health concern, where prompt access to automated external defibrillators (AEDs) significantly improves survival. This scoping review broadly investigates the feasibility and impact of dronedelivered AEDs for OHCA response.
Methods: PubMed, Cochrane, and Web of Science were searched from inception to August 6, 2024, with eligibility broadly including empirical data.
Front Neurol
December 2024
Department of Tuina and Rehabilitation Medicine, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, China.
Background: Amyotrophic lateral sclerosis (ALS) is a chronic, progressive disease that affects both upper and lower motor neurons. Some physicians have used traditional Chinese therapies (TCT) to treat ALS. However, there has been no systematic review or meta-analysis to evaluate the effectiveness and safety of TCT interventions.
View Article and Find Full Text PDFSports Med Health Sci
March 2025
FPCEE-Blanquerna, Ramon Llull University, Barcelona, Spain.
Impairments on body function, activities of daily living (ADL) and cognition are common after stroke. Eccentric resistance training (ERT) may be implemented to improve them. The primary objectives were to evaluate whether ERT improves body function, ADL and cognition after stroke.
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