In the title compound, [Zn(C(6)H(5)N(2)O(2))(2)(H(2)O)]·3H(2)O, the Zn(II) centre is five-coordinated by two O,N-bidentate Schiff base ligands and one O atom from a water mol-ecule in a slightly distorted square-pyramidal geometry. In the crystal, the complex and uncoordinated water mol-ecules are linked by O-H⋯O, O-H⋯N and C-H⋯O hydrogen bonds, forming a three-dimensional network.
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http://dx.doi.org/10.1107/S1600536809031778 | DOI Listing |
J Oral Biosci
December 2024
Department of Maxillofacial Orthognathics, Division of Maxillofacial and Neck Reconstruction, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, 1-5-45, Bunkyo-ku, Tokyo, 113-8549, Japan.
Objectives: To investigate the effects of hypoxia on tooth germ development in mice and explore the underlying mechanisms.
Methods: Tooth germs were extracted from E14.5 mouse embryos and divided into the control and hypoxia groups for organ culture.
Gels
December 2024
College of Pharmacy and Inje Institute of Pharmaceutical Sciences and Research, Inje University, 197 Inje-ro, Gimhae 50834, Republic of Korea.
The objective of this work was to develop a supersaturated gel formulation (SGF) loaded with the maximum atorvastatin calcium trihydrate (ATR) dose. The maximum dose strength of ATR needs to be reduced through improving solubility and dissolution rate to mitigate side effects due to the necessity of taking high doses. ATR has highly pH-dependent solubility at 37 °C, leading to poor solubility (<10 μg/mL) in stomach acid (pH 1.
View Article and Find Full Text PDFChem Pharm Bull (Tokyo)
December 2024
Department of Pharmaceutical Engineering, School of Pharmacy, Aichi Gakuin University.
A co-amorphous state composed of probucol (PC) and fluvastatin sodium salt (FLU) was prepared by spray-drying (SD). We have previously reported that PC and atorvastatin calcium trihydrate salt (ATO) formed a co-amorphous state when prepared by a SD method and that the solubility of PC and the amorphous stability were improved by the preparation of the co-amorphous state. In the present study, the physicochemical properties, including the amorphous stability of the prepared co-amorphous state, were characterized.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Division of Microbiology & Pharmaceutical Biotechnology, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India. Electronic address:
Antimicrobial buccal hydrogel made of polymers have gained tremendous utilisation in biomedical field. Dual drug loaded, porous materials are important areas of research for medical and pharmaceutical industries. In this regard, a series of hydrogels (F1, F2, F3) were prepared with gum odina and carbopol 940 in aqueous solution with calcium chloride as the cross linker and glycerol as plasticizer by ionotropic gelation method.
View Article and Find Full Text PDFSci Rep
November 2024
Department of Orthopedics, Gusu School, Nanjing Medical University, The First People's Hospital of Kunshan, Suzhou, Jiangsu, China.
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