Ultra high vacuum scanning tunnelling microscopy revealed chlorosubphthalocyanine to self-organize into discrete well-defined bilayer and trilayer triangular nanocrystallites when evaporated onto a Cu(111) surface.
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http://dx.doi.org/10.1039/c1cc11658d | DOI Listing |
Chem Commun (Camb)
January 2022
Department of Organic Chemistry and Institute for Advanced Research in Chemical Sciences (IadChem), Universidad Autónoma de Madrid, Calle Francisco Tomás y Valiente, 7, Madrid 28049, Spain.
A subphthalocyanine substituted with nine tetra(ethylene glycol) chains on the periphery has been synthesised. This novel amphiphilic and cone-shaped compound can self-assemble in water into spherical nanoparticles with a hydrodynamic diameter of 154 nm. These nanoparticles can be taken up readily by cancer cells and localised predominately in lysosomes where they disassemble gradually, leading to activation in fluorescence emission and, photocytotoxicity, showing IC values of as low as 1.
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September 2011
Universidad Autónoma de Madrid, Departamento de Física de la Materia Condensada, Campus de Cantoblanco, Madrid, Spain.
Ultra high vacuum scanning tunnelling microscopy revealed chlorosubphthalocyanine to self-organize into discrete well-defined bilayer and trilayer triangular nanocrystallites when evaporated onto a Cu(111) surface.
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