Multiscale modeling is increasingly being recognized as a promising research area in computational cancer systems biology. Here, exemplified by two pioneering studies, we attempt to explain why and how such a multiscale approach paired with an innovative cross-scale analytical technique can be useful in identifying high-value molecular therapeutic targets. This novel, integrated approach has the potential to offer a more effective in silico framework for target discovery and represents an important technical step towards systems medicine.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092304 | PMC |
| http://dx.doi.org/10.1002/ddr.20401 | DOI Listing |
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