Background: Little is known about the relative impact of different mental disorders on adult quality of life (QOL). This study estimated associations between several mental disorders and QOL in a representative American community sample.
Methods: The QOL instrument was administered to 640 adult participants in the Children in the Community Study, a population-based longitudinal study. DSM-Axis I and Axis II mental disorder diagnoses were assessed by psychiatric interview.
Results: Poorer QOL was strongly associated with having a mood disorder, especially major depression disorder (MDD) (effect size, ES = -0.57, p < 0.01), whereas poorer quality social relationships were associated with having dysthymia and bipolar disorders (ES = -0.92, p < 0.01; ES = -0.80, p < 0.05, respectively). Most anxiety disorders were not independently related to QOL with the exception of post traumatic stress disorder (PTSD), which was significantly related to poorer physical health (ES = -0.78, p < 0.01) and psychological well-being (ES = -0.73, p < 0.01) and to less overall QOL (ES = -0.57, p < 0.01).
Conclusions: MDD and PTSD are independently related to impaired QOL and dysthymia and bipolar disorder negatively influence social relationships.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433573 | PMC |
| http://dx.doi.org/10.1016/j.jad.2011.01.010 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effectiveness of Traditional Chinese Medicine in Psychological Rehabilitation After Lung Cancer Surgery: Systematic Review and Meta-Analysis protocol.
Integr Cancer Ther
January 2025
Guang 'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Article Synopsis
- Lung cancer has the highest incidence and mortality rates globally, making effective post-surgical mental health support crucial due to associated challenges like anxiety and depression.
- Traditional Chinese medicine shows promise in improving psychological well-being and physical symptoms after lung cancer surgery, but its effectiveness specifically for mental function recovery needs investigation.
- The study will systematically review various databases for randomized controlled trials focusing on depression and anxiety after lung cancer surgery, assessing data quality and outcomes using established evaluation tools.
Preliminary Evidence for Perturbation-Based tACS-EEG Biomarkers of Gamma Activity in Alzheimer's Disease.
Int J Geriatr Psychiatry
January 2025
Precision Neuroscience & Neuromodulation Program, Gordon Center for Medical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Background: Alzheimer's disease (AD) is characterized by impaired inhibitory circuitry and GABAergic dysfunction, which is associated with reduced fast brain oscillations in the gamma band (γ, 30-90 Hz) in several animal models. Investigating such activity in human patients could lead to the identification of novel biomarkers of diagnostic and prognostic value. The current study aimed to test a multimodal "Perturbation-based" transcranial Alternating Current Stimulation-Electroencephalography (tACS)-EEG protocol to detect how responses to tACS in AD patients correlate with patients' clinical phenotype.
View Article and Find Full Text PDFInsomnia Prevalence and Correlates in Cancer Patients Undergoing Treatment.
Psychooncology
January 2025
Department of Psychiatry, Boston Children's Hospital, Boston, Massachusetts, USA.
Background: Insomnia is the most common sleep disturbance among cancer patients undergoing active treatment. If untreated, it is associated with significant physical and psychological health consequences. Prior efforts to determine insomnia prevalence and correlates have primarily assessed patients in clinical trials, in limited disease groups, and excluding important patient subgroups.
View Article and Find Full Text PDFEffects of lithium carbonate combined with olanzapine on glucose and lipid metabolism in the treatment of bipolar disorder and gender differences.
Pak J Pharm Sci
January 2025
Department of Psychiatry, the Fifth People's Hospital of Luoyang, Luoyang City, Henan Province.
To explore the effect of lithium carbonate combined with olanzapine on glucose and lipid metabolism, as well as gender differences in treating bipolar disorder (BD). 110 BD patients admitted to the Fifth People's Hospital of Luoyang from February 2022 to January 2024 were retrospectively included in the study. Patients were categorized into two groups based on treatment: The single group (lithium carbonate, n = 50) and the coalition group (lithium carbonate + olanzapine, n=60).
View Article and Find Full Text PDFTherapeutic effects of chiglitazar combined with Rosa roxburghii Tratt. in inpatients with antipsychotic-induced metabolic syndrome.
Pak J Pharm Sci
January 2025
Department of Psychiatry, Wenzhou Seventh People's Hospital, Wenzhou, China.
The objective of this study was to evaluate the therapeutic effects of Chiglitazar combined with Rosa roxburghii Tratt (RRT) in inpatients diagnosed with psychiatric disorders and antipsychotic-induced metabolic syndrome (MetS).100 cases were included and divided into the Siglitazar group (n=50) and the Siglitazar + RRT group (n=50) Anthropometric measurements, lipid and glucose metabolism indicators, inflammatory markers and PANSS scores were assessed at baseline, 8 weeks and 12 weeks post-treatment. Both treatment groups exhibited significant reductions in waist circumference and improvements in lipid profiles and glucose metabolism indicators over the 12-week study period.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!