AI Article Synopsis
- The study focused on investigating polyuria, a common side effect of long-term lithium treatment, in 56 patients with bipolar disorder.
- Approximately 70% of the participants exhibited polyuria, with most cases going unreported unless specifically asked about.
- The research highlighted that polyuria significantly affected the patients' daily lives and work due to increased urine output, underlining the need for better awareness and management of this issue.
Article Abstract
Lithium-induced polyuria, although common, often goes unrecognized. The purpose of the present study was therefore to investigate the complaints of polyuria, and distress and functional impairment associated with polyuria, in 56 patients with bipolar disorder on long-term lithium treatment. All participants underwent 24-h urine collection, and renal function tests. Polyuria (24-h urine volume > 3 L) was found in 70% of subjects. Unless directly enquired about, polyuria was underreported. Impairment in work and daily routine due to increased urine output/frequency was associated with 24-h urine volumes. Polyuria is a highly prevalent, distressing and impairing side-effect of long-term lithium treatment, requiring due attention.
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| http://dx.doi.org/10.1111/j.1440-1819.2011.02214.x | DOI Listing |
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