Introduction: Consequences of heroin abuse include organic damage of cerebral structures. The level of impairments is in a direct and positive relation with the length of heroin abuse.
Objective: The aim of this research was the evaluation of the reaction time with heroin addicts with different length of substance abuse.
Research Method: 90 examinees were divided into three groups with relation to the length of heroin abuse. Data collection included a questionnaire referring to socio-demographic and addictive characteristics. A specially designed programme was used for the evaluation of reaction time to audio/ visual signal.
Results: In relation to the reaction time as overall model, the difference between examinees with different length of heroin abuse can be found on the marginal level of significance (F = 1.69; df = 12; p = 0.07). In visual modality, with the increase of length of heroin abuse leads to a significant prolongation of simple (the first visual sign: F = 3.29; df = 2; p = 0.04) and choice reaction time (the second visual sign: F = 4.97; df = 2; p = 0.00; the third visual sign: F = 3.08; df = 2; p = 0.05). Longer heroin consumption also leads to the prolongation of the simple (the first auditory task: F = 3.41; df = 2; p = 0.04) and the complex auditory reaction time (the second auditory task: F = 5.67; df = 2; p = 0.01; the third auditory task: F = 6.42; df = 2; p = 0.00).
Conclusion: Heroin abuse leads to the prolongation of both simple and choice reaction time in visual as well as auditory modality. The average daily dose of opiates was the most important predictor of the abovementioned cognitive dysfunction.
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http://dx.doi.org/10.2298/sarh1102069m | DOI Listing |
PLoS One
January 2025
Departamento de Psicología Evolutiva y Comunicación, Campus Universitario de Vigo, University of Vigo, Vigo, Spain.
The main purpose of this study was to examine the age-related changes in inhibitory control of 450 children at the ages of 7-8, 11-12, and 14-16 when controlling for working memory capacity (WMC) and processing speed to determine whether inhibition is an independent factor far beyond its possible reliance on the other two factors. This examination is important for several reasons. First, empirical evidence about age-related changes of inhibitory control is controversial.
View Article and Find Full Text PDFNeurochem Res
January 2025
Department of Neurology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, 226001, China.
Our aim was to evaluate the regulation of messenger RNAs (mRNAs) and biological pathways by long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) in ischemic stroke. We employed weighted gene co-expression network analysis (WGCNA) to construct two co-expression networks for mRNAs with circRNAs and lncRNAs, respectively, to investigate their association with ischemic stroke. We compared the overlap of mRNAs and biological pathways in the stroke-associated modules of the two networks.
View Article and Find Full Text PDFTrop Anim Health Prod
January 2025
Department of Agricultural Biotechnology, Faculty of Agriculture, Kırşehir Ahi Evran University, 40100, Kirsehir, Türkiye.
The present study was conducted on specific skeletal muscles of six weaned male kids from each of the Angora, Hair, Honamlı, and Kilis goat breeds. The relationships between the expression of myogenic factor 5 (Myf5) and myogenic factor 6 (Myf6) genes and muscle fibre characteristics were analysed. Muscle samples from the longissimus dorsi (LD) and semitendinosus (ST) were collected from six 90-day-old weaned male kids of each breed.
View Article and Find Full Text PDFNanoscale
January 2025
Department of Chemistry, Indian Institute of Technology Patna, Patna 801106, Bihar, India.
Covalent organic frameworks (COFs) are crystalline porous materials bearing well-ordered two- or three-dimensional molecular tectons in their polymeric skeletal framework. COFs are structurally robust as well as physiochemically stable. Currently, these are being developed for their use as "heterogeneous catalysts" for various organic transformations.
View Article and Find Full Text PDFUnlabelled: Antibiotic resistance is frequently observed shortly after the clinical introduction of an antibiotic. Whether and how frequently that resistance occurred before the introduction is harder to determine, as isolates could not have been tested for resistance before an antibiotic was discovered. Historical collections, like the British National Collection of Type Cultures (NCTC), stretching back to 1885, provide a window into this history.
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