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Functional analysis of AtDPBF3, encoding a key member of the ABI5 subfamily involved in ABA signaling, in Arabidopsis thaliana under salt stress.
Plant Physiol Biochem
January 2025
School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, 200240, China. Electronic address:
Soil salinization is a major environmental stress limiting plant growth and development, affecting crop yields worldwide. We investigated the role of AtDPBF3, encoding a key member of the ABI5 subfamily, in the response to salt stress. The AtDPBF3 mutant (dpbf3) was significantly more sensitive to salt stress compared with wild type.
View Article and Find Full Text PDFAntibiotic resistance genes in the coastal atmosphere under varied weather conditions: Distribution, influencing factors, and transmission mechanisms.
Environ Pollut
January 2025
Key Laboratory of Marine Chemistry Theory and Technology, Ministry of Education, Ocean University of China, Qingdao, 266100, PR China; College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao, 266100, PR China. Electronic address:
Antibiotic resistance genes (ARGs) have escalated to levels of concern worldwide as emerging environmental pollutants. Increasing evidence suggests that non-antibiotic antimicrobial substances expedite the spread of ARGs. However, the drivers and mechanisms involved in the generation and spread of ARGs in the atmosphere remain inadequately elucidated.
View Article and Find Full Text PDFDifferent regulative effects of high- and low-frequency external trigeminal nerve stimulation (eTNS) on sleep activity: Preliminary study.
Sleep Med
January 2025
Engineering Research Center of Molecular and Neuro Imaging of the Ministry of Education, School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710126, China; Intelligent Non-invasive Neuromodulation Technology and Transformation Joint Laboratory, Xidian University, Xi'an, Shaan xi, 710126, China; Guangzhou Institute of Technology, Xidian University, Xi'an, Shaanxi, China.
Study Objective: With the growing prominence of peripheral nerve stimulation technology, the clinical applications and potential neurophysiological mechanisms of external trigeminal nerve stimulation (eTNS) have garnered increasing attention. Despite its status as the sole neuromodulation method commonly employed in sleep, no studies have explored the effects of eTNS at varying frequencies on sleep activities. This study aims to investigate the regulatory effects of high-frequency and low-frequency eTNS on sleep activities using polysomnography.
View Article and Find Full Text PDFMetagenomic insight into the enrichment of antibiotic resistance genes in activated sludge upon exposure to nanoplastics.
Environ Pollut
December 2024
Hunan Province Key Laboratory of Rare Metal Minerals Exploitation and Geological Disposal of Wastes, School of Resources Environment and Safety Engineering, University of South China, Hengyang, 421001, China. Electronic address:
Activated sludge is an important reservoir for the co-occurring emerging contaminants including nanoplastics (NPs) and antibiotic resistance genes (ARGs). However, the impacts and potential mechanisms of NPs on the fate of ARGs in activated sludge are not fully understood. Herein, we used metagenomic approach to investigate the responses of ARGs, host bacteria, mobile genetic elements (MGEs), and functional genes to polystyrene (PS) NPs at environmentally relevant (0.
View Article and Find Full Text PDFSPROUTY2, a Negative Feedback Regulator of Receptor Tyrosine Kinase Signaling, Associated with Neurodevelopmental Disorders: Current Knowledge and Future Perspectives.
Int J Mol Sci
October 2024
Department of Life Sciences, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Growth-factor-induced cell signaling plays a crucial role in development; however, negative regulation of this signaling pathway is important for sustaining homeostasis and preventing diseases. SPROUTY2 (SPRY2) is a potent negative regulator of receptor tyrosine kinase (RTK) signaling that binds to GRB2 during RTK activation and inhibits the GRB2-SOS complex, which inhibits RAS activation and attenuates the downstream RAS/ERK signaling cascade. SPRY was formerly discovered in but was later discovered in higher eukaryotes and was found to be connected to many developmental abnormalities.
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