[Prevalence of diverticulosis and colon tumors among adult population of Moscow with constipation and symptoms of anxiety (according to population-based study MUSA)].

Unlabelled: Aim was to assess the diagnostic value of the alarm symptoms (AS's) in subjects with constipation based on prospective examination of adult population.

Material & Methods: Data was collected from 1189 randomly selected subjects older than 18 y.o. we used specially designed Questionnaire, which included questions for constipation and AS's (such as rectal bleeding, weight loss, permanent intensive abdominal pain, fever and family history of colorectal cancer (CRC)). Subjects with either constipation or AS (s) were offered to do endoscopy.

Results: Any of the AS (s) was registered in 11.3%. After survey 300 subjects were supposed to do endoscopy. 222 (74%) subjects agreed to be undergone rectoscopy and colonoscopy. The prevalence of colon diverticulosis was 16.2%, the prevalence of colorectal polyp (s)--10.8%, CRC--4.5%. The highest predictive value for CRC had the combination of symptoms: rectal bleeding+family history of CRC--50%, the lowest--abdominal pain (4.8%).

Conclusion: The combination of symptoms: rectal bleeding + family history of CRC has the highest predictive value for CRC.