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http://dx.doi.org/10.1038/473158a | DOI Listing |
Parasit Vectors
January 2025
Center of Excellence in Veterinary Parasitology, Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Background: The subfamily Phlebotominae comprises 1028 species of sand fly, of which only 90 are recognized as vectors of pathogenic agents such as Trypanosoma, Leishmania, and Bartonella. In Thailand, leishmaniasis-a sand fly-borne disease-is currently endemic, with 36 documented sand fly species. However, many cryptic species likely remain unidentified.
View Article and Find Full Text PDFBMC Genomics
January 2025
Botany and Mycology Unit, Finnish Museum of Natural History, University of Helsinki, Helsinki, Finland.
Background: Improving the germination performance of bread wheat is an important breeding target in many wheat-growing countries where seedlings are often established in soils with high salinity levels. This study sought to characterize the molecular mechanisms underlying germination performance in salt-stressed wheat. To achieve this goal, a genome-wide association study (GWAS) was performed on 292 Iranian bread wheat accessions, including 202 landraces and 90 cultivars.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Pharmacy, Affiliated Hospital of Southwest Jiao Tong University, The Third People's Hospital of Chengdu, Chengdu, 610014, China.
The pathogenesis of metabolic dysfunction-associated steatotic liver disease (MASLD) remains unclear due to the complexity of its etiology. The emerging field of the epitranscriptome has shown significant promise in advancing the understanding of disease pathogenesis and developing new therapeutic approaches. Recent research has demonstrated that N4-acetylcytosine (ac4C), an RNA modification within the epitranscriptome, is implicated in progression of various diseases.
View Article and Find Full Text PDFSci Rep
January 2025
Faculty of Electronic Information and Physics, Central South University of Forestry and Technology, Changsha, 410004, Hunan, China.
Accurate segmentation of retinal blood vessels from retinal images is crucial for detecting and diagnosing a wide range of ophthalmic diseases. Our retinal blood vessel segmentation algorithm enhances microfine vessel extraction, improves edge texture clarity, and normalizes vessel distribution. It stabilizes neural network training for complex retinal vascular features.
View Article and Find Full Text PDFSci Rep
January 2025
College of Electrical and Information Engineering, Hunan Institute of Traffic Engineering, Hunan, Hengyang, 421001, China.
This study aims to explore the application value of big data technology (BDT) in enterprise information security (EIS). Its goal is to develop a risk prediction model based on big data analysis to enhance the information security protection capability of enterprises. A big data analysis system that can monitor and intelligently identify potential security risks in real-time is constructed by designing complex network analysis algorithms and machine learning models.
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