Objective: To modify the method of analysis of urinary diethyl phosphate (DEP) in order to determine the relationship between atmospheric ethion concentration and urinary DEP concentration.
Materials And Method: A cross-sectional study was conducted by collecting atmospheric ethion in the breathing zone of 28 farmers following the NIOSH 5600 method. Urine samples were also collected to analyze urinary DEP concentrations by a modified method using a Gas Chromatography-Flame Photometric Detector (FPD).
Results: The average atmospheric ethion concentration in the breathing zone of farmers was 0.036 +/- 0.018 mg/m3. The average urinary DEP in pre-shift and post-shift was 0.030 +/- 0.06 and 0.851 +/- 1.80 mg/g of creatinine respectively. The average DEP during work shifts was 0.53 +/- 0.27, and ranged from 0.12 to 1.16 mg/g of creatinine. A high correlation coefficient (r = 0.645) was found between atmospheric ethion concentrations and urinary DEP concentrations at p < 0.001.
Conclusion: The modified method provided a reliable result and the urinary DEP during work shifts was found to be a reliable biomarker of ethion exposure.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Neurobehavioral Performance in Preschool Children Exposed Postnatally to Organophosphates in Agricultural Regions, Northern Thailand.
Toxics
November 2024
Department of Community Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Evidence of the effects of postnatal exposure to organophosphates (OPs) on children's neurodevelopment remains limited but crucial. This cross-sectional study evaluated exposure to OPs and neurobehavioral performance in 172 preschool children. Urinary dialkyl phosphate (DAP) metabolites, biomarkers for exposure to OPs, were measured.
View Article and Find Full Text PDFAssociations between pre- and post-natal exposure to phthalate and DINCH metabolites and gut microbiota in one-year old children.
Environ Pollut
December 2024
Environmental Epidemiology Applied to Development and Respiratory Health Team, Institute for Advanced Biosciences, Inserm U1209, CNRS UMR 5309, University Grenoble Alpes, 38000, Grenoble, France; SMILE, Institut de Biologie de l'ENS (IBENS), Ecole Normale Supérieure, Université PSL, CNRS, INSERM, F-75005, Paris, France; PARSEC, Ecole Normale Supérieure, Université PSL, CNRS, INSERM, F-75005, Paris, France.
The gut microbiota is a collection of symbiotic microorganisms in the gastrointestinal tract. Its sensitivity to chemicals with widespread exposure, such as phthalates, is little known. We aimed to investigate the impact of perinatal exposure to phthalates on the infant gut microbiota at 12 months of age.
View Article and Find Full Text PDFExposure to Phthalates and Alternative Plasticizers in Patients with Impaired Kidney Function in Korea: Temporal Trend during 2011-2020 and Its Association with Chronic Kidney Disease.
Environ Sci Technol
October 2024
Graduate School of Public Health, Seoul National University, Seoul 08826, Republic of Korea.
Phthalates are chemical risk factors of chronic kidney disease (CKD); however, little is known about temporal trends of phthalate exposure and associated health risks among CKD patients. Such information is even scarce for alternative plasticizers. CKD patients were recruited from 2011 to 2020 in Korea ( = 200) and assessed for the temporal changes of both traditional and alternative plasticizer exposure.
View Article and Find Full Text PDFAssociation between phthalates exposure and non-alcoholic fatty liver disease under different diagnostic criteria: a cross-sectional study based on NHANES 2017 to 2018.
Front Public Health
October 2024
Department of Laboratory Medicine, Shenzhen Institute of Translational Medicine, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen Key Laboratory of Medical Laboratory and Molecular Diagnostics, Shenzhen, China.
Article Synopsis
- - The study investigates the link between non-alcoholic fatty liver disease (NAFLD) and urinary phthalate metabolites, considering the rise of phthalate substitutes and variations in diagnostic approaches.
- - Analyzing data from 641 participants in the NHANES 2017-2018 database, researchers used three methods to diagnose NAFLD and assessed the concentration of various phthalate metabolites in urine.
- - Significant correlations were found between NAFLD and certain phthalate metabolites through logistic regression analysis, emphasizing the need for precise diagnostics in understanding NAFLD's development.
Relationship between phthalate exposure and kidney function in Taiwanese adults as determined through covariate-adjusted standardization and cumulative risk assessment.
Ecotoxicol Environ Saf
October 2024
School of Public Health, National Defense Medical Center, Taipei, Taiwan. Electronic address:
Article Synopsis
- The study investigated the relationship between phthalate exposure and kidney function in adults, analyzing data from 839 participants in the Taiwan Biobank.
- Researchers measured urinary levels of 10 phthalate metabolites and assessed kidney function through biomarkers like blood urea nitrogen (BUN) and estimated glomerular filtration rate (eGFR).
- Findings revealed significant associations where higher levels of certain phthalate metabolites were linked to impaired kidney function indicators, implying that increased exposure to environmental phthalates may negatively impact kidney health.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!