Gallstone disease (GSD) in childhood is no longer a casuistry. In connection with it pediatricians have some questions: which method of treatment should be preferred? How to prevent disease progression? Despite the vast experience gained by physicians, gastroenterologists in the study of cholelithiasis in pediatric pharmacotherapy issues of GSD are under study, because it isn't possible to extrapolate the turned internists data in pediatrics, should be considered with the anatomical and physiological characteristics of children, to take into account peculiarities of formation and chemical composition of gallstones. Recent advances in operative and endoscopic techniques allow for the revision of treatment policy for children with cholelithiasis. The aim of the study was to determine the effectiveness of conservative therapy of gallstone disease in infants. Materials and methods. We observed 74 children with cholelithiasis in age from birth to 3 years. Was shown efficiency of gallstones litholysis with help of ursodeoxycholic acid.

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