Objective: To study the effects of oviductus rana on the alleviation of physical fatigue in rats and their mechanisms.
Methods: 64 Kunming male rats were divided into 4 groups by random: the control group and 3 oviductus rana groups, 16 mice in each group. Oviductus rana homogenates at 1, 5 and 10 times of dosage used for the adults (6 g/60 kg BW) were given by gavage for the low, medium and high dose oviductus rana groups for 21 days. The rats in the control group were given normal saline by gavage. A loaded swimming test was carried on 8 rats of each group at one hour after the last gavage. The other 8 rats in each group were swimming for 30 minutes and blood, liver and muscle samples were taken after resting for 30 minutes. Blood sugar, blood urea nitrogen and blood lactic acid, hepatic glycogen and muscle glycogen were examined.
Results: The swimming time insisted in the loaded swimming test in oviductus rana groups was higher than that in the control group (P < 0.05, P < 0.01); the content of blood urea nitrogen and lactic acid in the oviductus rana groups was dropped and lower than the control group (P < 0.05, P < 0.01); the content of blood sugar, hepatic glycogen and muscle glycogen was raised and higher than the control group (P < 0.05, P < 0.01).
Conclusion: There is an effect of Oviducts Rana on alleviating physical fatigue in mice.
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