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Assessment of oral health status among occupational chefs and pantry workers in Hyderabad city.
J Educ Health Promot
December 2024
Department of Public Health Dentistry, Kamineni Institute of Dental Sciences and Research Centre, Narketpally, Nalgonda, Telangana, India.
Background: The chefs and pantry workers environment plays a crucial role in the general and oral health. These workers have some unusual work timings and have a lot of stress and anxiety, and they also consume tobacco, alcohol, and smoke the cigarettes, which has a greater impact on oral health.
Material And Methods: A total of 86 kitchen workers (53 chefs and 33 pantry workers) of ten well-known restaurants in Hyderabad city were included.
Long-term smoking contributes to aging frailty and inflammatory response.
Biomol Biomed
January 2025
China Tobacco Sichuan Industrial Co., Ltd., Chengdu, China; Harmful Components and Tar Reduction in Cigarette Key Laboratory of Sichuan Province, Chengdu, China; Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
In recent years, the health challenges linked to frailty in the elderly, particularly those worsened by cigarette smoke, have become more pronounced. However, quantitative studies examining the impact of smoking dosage on frailty in this population remain limited. To address this gap, we developed a model using smoke-exposed elderly mice.
View Article and Find Full Text PDFExploring dental students' knowledge on oral cancer prevention: a cross-sectional study in Moldova, Armenia, and Belarus.
BMC Oral Health
January 2025
Department of Clinical Medicine, University of Bergen, Bergen, 5020, Norway.
Background: Survival rate of patients with oral cancer (OC) remains to be very low despite advancements in therapy and surgical techniques. This is attributed to the fact that most OC cases are discovered at a late stage. Dentists play a vital role in early detection of OC through oral mucosal examination, and in informing the patients about avoidable risk factors of the disease, such as tobacco and excessive alcohol use.
View Article and Find Full Text PDFCD137 agonism enhances anti-PD1 induced activation of expanded CD8 T cell clones in a neoadjuvant pancreatic cancer clinical trial.
iScience
January 2025
Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Successful pancreatic ductal adenocarcinoma (PDAC) immunotherapy requires therapeutic combinations that induce quality T cells. Tumor microenvironment (TME) analysis following therapeutic interventions can identify response mechanisms, informing design of effective combinations. We provide a reference single-cell dataset from tumor-infiltrating leukocytes (TILs) from a human neoadjuvant clinical trial comparing the granulocyte-macrophage colony-stimulating factor (GM-CSF)-secreting allogeneic PDAC vaccine GVAX alone, in combination with anti-PD1 or with both anti-PD1 and CD137 agonist.
View Article and Find Full Text PDFComparing the Doppler flow parameters of orbital vessels among healthy nonsmokers, diabetic nonsmokers, and diabetic smokers visiting a tertiary health-care center.
Taiwan J Ophthalmol
November 2024
Department of Ophthalmology, KVG Medical College and Hospital, Sullia, Karnataka, India.
Purpose: The present study aimed to assess the impact of diabetes mellitus and smoking in orbital vessels, utilizing resistive index (RI) through color Doppler imaging (CDI).
Materials And Methods: The cross-sectional study consisted of 90 participants divided into three groups of 30 each. Group A consisted of normal individuals, Group B consisted of patients with diabetes, and Group C consisted of patients with a history of diabetes and smoking.
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