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Programmed Transformation of Osteogenesis Microenvironment by a Multifunctional Hydrogel to Enhance Repair of Infectious Bone Defects.
Adv Sci (Weinh)
January 2025
Orthopedic Institute, Department of Orthopedic Surgery, Medical 3D Printing Center, The First Affiliated Hospital, Changzhou Geriatric hospital, MOE Key Laboratory of Geriatric Diseases and Immunology, School of Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, Jiangsu, 215000, P. R. China.
Repair of infectious bone defects remains a serious problem in clinical practice owing to the high risk of infection and excessive reactive oxygen species (ROS) during the early stage, and the residual bacteria and delayed Osseo integrated interface in the later stage, which jointly creates a complex and dynamic microenvironment and leads to bone non-union. The melatonin carbon dots (MCDs) possess antibacterial and osteogenesis abilities, greatly simplifying the composition of a multifunctional material. Therefore, a multifunctional hydrogel containing MCDs (GH-MCD) is developed to meet the multi-stage and complex repair needs of infectious bone injury in this study.
View Article and Find Full Text PDFThe effect of instability resistance training on balance ability among athletes: a systematic review.
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Department of Sport Studies, Faculty of Educational Studies, University Putra Malaysia, Serdang, Selangor, Malaysia.
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View Article and Find Full Text PDFA meta-analysis of the effect of physical activity programs on fundamental movement skills in 3-7-year-old children.
Front Public Health
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Department of Physical Education, Shandong Normal University, Jinan, China.
Introduction: This study aimed to systematically review the effects of different physical activity programs on the fundamental movement skills of 3 - 7-year-old children.
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Front Public Health
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Department of Health Administration, Kongju National University of Nursing and Health, Kongju, Republic of Korea.
Adolescents worldwide are increasingly affected by mental health disorders, with anxiety disorders, including Generalized Anxiety Disorder (GAD), being particularly prevalent. Despite its significant impact, GAD in adolescents often remains underdiagnosed due to vague symptoms and delayed medical attention, highlighting the need for early diagnosis and prevention strategies. This study utilized data from the Korea Youth Risk Behavior Web-based Survey (KYRBS) from 2020 to 2023 to analyze factors influencing GAD in adolescents.
View Article and Find Full Text PDFEffects of fermented on the intestinal microbiota and metabolites of Hu lambs with naturally infected with spp.
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College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Background: Sheep coccidiosis could disturb the balance of intestinal microbiota, causing diarrhea, and even death in lambs. Chemical drugs are the primary method of treating sheep coccidiosis, but their use will bring drug resistance, toxic side effects, drug residues, and other problems. Chinese herbal medicines are investigated as alternative methods for controlling coccidian infections.
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