Background: The purpose of this study is to determine if the three-step Luria test is useful for differentiating between cognitive disorders.
Methods: A retrospective record review of performance on the three-step Luria test was conducted on 383 participants from a university-based dementia clinic. The participants ranged in their diagnosis from frontotemporal dementia (FTD; n = 43), Alzheimer disease (AD; n = 153), mild cognitive impairment (MCI; n = 56), and normal controls (NC; n = 131). Performance of the Luria test was graded as normal or abnormal.
Results: An abnormal test occurred in 2.3% of NC, 21.4% of MCI, 69.8% of FTD, and 54.9% of AD subjects. The frequency of abnormal tests in all diagnostic groups increased with functional impairment as assessed by the Clinical Dementia Rating scale (CDR). When CDR = 3 (severe), 100% of the FTD and 72.2% of the AD subjects had abnormal Luria tests.
Conclusions: The three-step Luria test distinguished NC and persons with MCI from FTD and AD, but did not distinguish FTD from AD subjects.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399685 | PMC |
| http://dx.doi.org/10.1017/S1041610211000767 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Precision Opioid Prescription in ICU Surgery: Insights from an Interpretable Deep Learning Framework.
J Surg (Lisle)
November 2024
Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Purpose: Appropriate opioid management is crucial to reduce opioid overdose risk for ICU surgical patients, which can lead to severe complications. Accurately predicting postoperative opioid needs and understanding the associated factors can effectively guide appropriate opioid use, significantly enhancing patient safety and recovery outcomes. Although machine learning models can accurately predict postoperative opioid needs, lacking interpretability hinders their adoption in clinical practice.
View Article and Find Full Text PDFResistant for Biodegradation of Diesel Fuel at High Concentration and Low Temperature.
Microorganisms
December 2024
Department of Civil and Environmental Engineering, University of Strathclyde, James Weir Building, Level 5, 75 Montrose Street, Glasgow G11XJ, UK.
The resistance of 16 strains to diesel fuel was studied. The minimal inhibitory concentrations of diesel fuel against were 4.0-64.
View Article and Find Full Text PDFVisual-Spatial Search in Neglect Syndrome as a Function of the Number of Stimuli in the Hemifields.
Healthcare (Basel)
November 2024
Faculty of Psychology, Lomonosov Moscow State University, Moscow 125009, Russia.
Background: Neglect syndrome is a serious condition that often affects the ability to perform visual-spatial search tasks, interfering with the ability to detect stimuli on the left side of space. A number of factors can affect the success of visual search in patients with neglect syndrome, including visual field load. The purpose of this study is to investigate how the number of stimuli in the right visual hemifield influences the efficiency of visual search in the left (neglected) hemifield, hypothesizing that an increased object load on the right side may impair search performance on the left.
View Article and Find Full Text PDFAssociation of Gait Impairment with Executive Dysfunction and Magnetic Resonance Imaging Brain Findings in Elderly Population.
J Assoc Physicians India
November 2024
Senior Resident, Department of Neurology, SMS Medical College, Jaipur, Rajasthan, India, Corresponding Author.
Article Synopsis
- The study aimed to explore the relationship between gait impairment, executive dysfunction (ED), and MRI brain findings in elderly individuals in India over a year-long observational study.
- Key risk factors for ED included hypertension, lipid profile issues, elevated serum creatinine, blood urea, and smoking, with smoking showing a particularly high risk.
- MRI results indicated brain atrophy in specific regions correlated with changes in gait parameters such as step length and stride width, emphasizing the interconnectedness of cognitive function and physical mobility in the elderly.
Long-Term Follow-Up of Neuropsychiatric Symptoms After Sustained Virological Response to Interferon-Free and Interferon-Based Hepatitis C Virus Treatment.
J Viral Hepat
November 2024
Department of Neurology, Hannover Medical School, Hannover, Germany.
Chronic hepatitis C virus (HCV) infection can be associated with neuropsychiatric symptoms like fatigue and cognitive impairment, independent of the liver status. The present study aims to assess changes in the pattern and extent of neuropsychological symptoms after successful treatment with interferon (IFN)-based and IFN-free therapy. HCV-infected patients who underwent neuropsychological assessment in previous studies were invited to a follow-up examination.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!