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Clinical and microbiological effectiveness of pulsed-xenon ultraviolet light disinfection in a neonatal intensive care unit in Japan.
J Hosp Infect
November 2024
Department of Neonatology, Gifu Prefectural General Medical Center, Gifu, Japan.
Background: Meticillin-resistant Staphylococcus aureus (MRSA) is a common causative agent of serious healthcare-related infections in neonatal intensive care units (NICUs). In adult ICUs, pulsed-xenon ultraviolet (PX-UV) disinfection of environmental surfaces, along with alcohol-based hand hygiene and terminal cleaning, has been demonstrated to reduce the MRSA acquisition rate.
Aim: To explore the impact of PX-UV use in NICUs on reducing MRSA transmission.
Isolation, genomic characterization and biotechnological evaluation of lactobacilli strains from chicken gastrointestinal tract.
Microb Pathog
November 2024
Yildiz Technical University, Faculty of Arts and Sciences, Department of Molecular Biology and Genetics, Istanbul, Turkey. Electronic address:
During a study investigating possible probiotics from chicken gut microbiota, strains C1-4 and C2-3 were isolated and identified as members of the genus Ligilactobacillus. The strains formed a well-supported cluster with Ligilactobacillus salivarius and Ligilactobacillus hayatikensis in phylogenetic trees. Their genomes, sized 1.
View Article and Find Full Text PDFPovidone-iodine and silver nitrate are equally effective in eradicating staphylococcal biofilm grown on a titanium surface: an in-vitro analysis.
J Hosp Infect
January 2025
'Sir John Charnley' Hip Surgery Unit, Institute of Orthopaedics 'Carlos E. Ottolenghi', Italian Hospital of Buenos Aires, Buenos Aires, Argentina. Electronic address:
Article Synopsis
- The study investigates which antibacterial solutions are most effective in eradicating biofilms formed by staphylococcal bacteria on titanium surfaces during DAIR surgery.
- Five antibacterial agents are tested: povidone-iodine, rifampicin, silver nitrate, copper sulphate, and chlorhexidine, focusing on their minimum biofilm eradication concentrations (MBEC) against both MSSA and MRSA strains.
- Results indicate that povidone-iodine and silver nitrate are significantly more effective, achieving at least 99.9% reduction in biofilm, compared to others like rifampicin and copper sulphate, which showed limited effectiveness.
Meticillin-resistant Staphylococcus aureus in the community-time to take action.
Clin Microbiol Infect
November 2024
Center for Microbiota Analysis and Therapeutics, Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.
Expert consensus on antimicrobial resistance research priorities to focus development and implementation of antibacterial vaccines and monoclonal antibodies.
Euro Surveill
November 2024
Infection Control Program, Geneva University Hospitals and Faculty of Medicine, WHO Collaborating Center, Geneva, Switzerland.
To reduce antimicrobial resistance (AMR), pathogen-specific AMR burden data are crucial to guide target selection for research and development of vaccines and monoclonal antibodies (mAbs). We identified knowledge gaps through previously conducted systematic reviews, which informed a Delphi expert consultation on future AMR research priorities and harmonisation strategies to support data-driven decision-making. Consensus (≥80% agreement) on importance and feasibility of research topics was achieved in two rounds, involving 24 of 39 and 19 of 24 invited experts, respectively.
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