Objectives: To evaluate the safety and efficacy of 120-W high-performance system (HPS) laser photoselective vaporization of the prostate (PVP) in the treatment of patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia.

Methods: Two experienced surgeons performed 120-W HPS laser PVP. The baseline characteristics, perioperative data, complications, and postoperative outcomes were evaluated at 3, 6, 12, 24, and 36 months postoperatively.

Results: A total of 550 consecutive patients, with a mean age of 67.6 years, underwent PVP with a 120-W HPS laser. The mean prostate volume was 72.93 cm3, with a mean prostate-specific antigen level of 3.57 ng/mL. The mean operative duration and the mean applied energy was 61.3 minutes and 164.06 kJ, respectively. No major complication occurred intraoperatively or postoperatively. The mean follow-up was 17.80 months. Significant improvements were observed postoperatively in the mean International Prostate Symptom Score, quality of life score, maximal urinary flow rate, and postvoid residual urine volume. The mean catheterization time was 18.5 hours. The complications included delayed hematuria in 26 (4.8%), recatheterization in 24 (4.4%), reoperation owing to residual prostatic adenoma in 46 (8.5%), urethral stricture in 19 (3.5%), and bladder neck contracture in 6 (1.1%) patients.

Conclusions: PVP with a 120-W HPS laser for benign prostatic hyperplasia has been proved to be a safe and effective procedure for our patients, including those treated with oral anticoagulants. The functional outcome in larger prostates was similar to that in smaller glands.

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http://dx.doi.org/10.1016/j.urology.2010.12.085DOI Listing

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  • - The study compares the effectiveness of 120 W HPS and 180 W XPS GreenLight laser systems for treating benign prostatic hyperplasia (BPH), revealing that the 180 W system has better operational efficiency and shorter catheterization times.
  • - Eight studies were analyzed, showing that while both systems had similar functional outcomes regarding prostate symptoms and urinary flow, the 180 W system resulted in improved quality of life and lower rates of complications.
  • - The findings suggest that the 180 W XPS laser is a more efficient and safer option for treating BPH, especially in larger prostates, and encourages further randomized trials to verify these results and investigate long-term effects.
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