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Renal Histopathological Changes in Children With Congenital Ureteropelvic Junction Obstruction.
Clin Pediatr (Phila)
February 2025
Department of Pediatric Surgery, St. John's Medical College Hospital, Bangalore, Karnataka, India.
Renal histologic changes in congenital ureteropelvic junction obstruction (UPJO), although well documented, are sparsely studied in children. This study aims to establish a histological grading depending on the glomerular and tubulo-interstitial changes in hydronephrotic kidneys and determine correlation with age at surgery and impact on function post-pyeloplasty. A renal cortical wedge biopsy was obtained after pyeloplasty and histological changes were graded from 1 to 4.
View Article and Find Full Text PDFPrediction of surgical necessity in children with ureteropelvic junction obstruction using machine learning.
Ir J Med Sci
January 2025
Faculty of Medicine, Department of Pediatric Surgery Division of Pediatric Urology, Eskisehir Osmangazi University, Eskişehir, Turkey.
Background: Hydronephrosis developing at the ureteropelvic junction due to obstruction poses clinical challenges as it has the potential to cause renal damage.
Aims: This study aims to evaluate how well machine learning models such, as XGBClassifier and Logistic Regression can be used to predict the need for treatment in patients, with hydronephrosis resulting from ureteropelvic junction obstruction.
Methods: Hydronephrosis was diagnosed in the medical records of patients from January 2015 to December 2020.
Zinner syndrome incidentally diagnosed in a man with ureteropelvic junction stone and hydronephrosis: A case report.
Urol Case Rep
January 2025
Department of Urology, China Medical University Hospital, Taiwan.
Zinner syndrome is a congenital anomaly characterized by seminal vesicle cysts, ipsilateral renal agenesis, and ejaculatory duct obstruction possibly associated with infertility. Only 200 cases of Zinner syndrome have been reported since its discovery in 1914. We present the case of a 63-year-old man seeking treatment for a ureteropelvic junction stone causing severe hydronephrosis.
View Article and Find Full Text PDFAnuric Acute Kidney Injury in Chronic Myeloid Leukemia: A Rare Complication Case.
Acta Med Indones
October 2024
Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
This report describes a rare case of anuric acute kidney injury related to suspected urate nephropathy in a 23-year-old male with chronic phase of Chronic Myeloid Leukemia (CML). The patient presented with anuria and limb edema, with a history of imatinib-treated CML. Investigations revealed probable urate crystals causing bilateral hydronephrosis and hydroureters.
View Article and Find Full Text PDFPosterior Urethral Valves and Fertility: Insight on Paternity Rates and Seminal Parameters.
Diseases
January 2025
Department of Urology, Magna Graecia University of Catanzaro, Viale Europa, 88100 Catanzaro, Italy.
Background: Posterior urethral valves (PUVs) represent the most common cause of male congenital lower urinary tract obstruction, often responsible for renal dysplasia and chronic renal failure. Despite recent improvements in patients' outcomes thanks to prenatal ultrasound early diagnosis, PUVs can still impact sexual function and fertility. This study aims to review the available evidence on fertility in PUV patients, examining paternity rates and semen parameters.
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