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Remote ischaemic conditioning for neurological disorders-a systematic review and narrative synthesis.
Syst Rev
December 2024
Department of Neuroscience, Geriatrics and Stroke, Sheffield Institute for Translational Neurosciences, University of Sheffield, Sheffield, UK.
Introduction: Remote ischaemic conditioning (RIC) refers to the use of controlled transient ischemic and reperfusion cycles, commonly of the upper or lower limb, to mitigate cellular damage from ischaemic injury. Preclinical studies demonstrate that RIC may have a neuroprotective effect and therefore could represent a novel therapeutic option in the management of neurological disorders. The aim of this review is to comprehensively describe the current clinical evidence of RIC in neurological disorders.
View Article and Find Full Text PDFRete anomaly of the middle cerebral artery: case series of 13 patients from the Northeastern United States.
J Neurointerv Surg
December 2024
Department of Neurology, Columbia University Irving Medical Center, New York, New York, USA.
Background: Rete middle cerebral artery (MCA) is a rare anomaly of the intracranial circulation that mimics congenital Moyamoya disease (MMD). Similar to MMD, it is reported almost exclusively in East-Asian ethnicities. Here, we report 13 patients with rete MCA anomaly from a predominantly non-Asian background in the USA.
View Article and Find Full Text PDFAnatomical Targeting of the Superior Cervical Ganglion on Computed Tomography Imaging for Guidance of Endovascular Transmural Intervention.
World Neurosurg
December 2024
Department of Neurosurgery, University of California Los Angeles, Los Angeles, California, USA. Electronic address:
Article Synopsis
- Endovascular transmural targeting of the superior cervical ganglion (SCG) is being explored as a minimally invasive method for delivering therapeutics, potentially beneficial for certain medical conditions due to its proximity to major cervical blood vessels.
- A retrospective study analyzed CT angiography from patients with head trauma or brain aneurysms to assess the dimensions of the SCG and its relationship to cervical vessels.
- Results indicated that 95% of SCGs are accessible via an endovascular approach from the internal carotid artery, which has the longest connection with the SCG, demonstrating the anatomical feasibility of this targeting method.
The effect of intravenous lidocaine infusion on subarachnoid anesthesia in patients undergoing total knee replacement: a randomised controlled trial.
J Anesth
November 2024
Department of Anesthesiology & Intensive Care, Maulana Azad Medical College and Associated Hospitals, New Delhi, 110002, India.
Purpose: Intravenous lidocaine is a non-opioid analgesic adjunct for perioperative pain relief. The aim of our study was to explore whether concurrent administration of intravenous lidocaine prolongs the duration of sensory block during total knee replacement (TKR) under spinal anaesthesia.
Methods: This prospective randomized double blind controlled trial was conducted on 28 patients (14 in lidocaine group and 14 in the control group) undergoing unilateral TKR under spinal anesthesia.
Ocular findings in the evaluation of abusive head trauma in children.
Saudi J Ophthalmol
September 2024
College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Purpose: Abusive head trauma (AHT) is a form of child physical abuse that can result in major ocular injuries. This study describes the clinical presentation and ocular manifestations of infants diagnosed with AHT in a tertiary care center in Saudi Arabia.
Methods: This is an observational, retrospective, cross-sectional study from 2015 to 2022 conducted at King Abdullah Specialized Children's Hospital (KASCH) in Riyadh, Saudi Arabia.
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