Sudden cardiac death is rare in children and adolescents but accounts for 19% to 30% of sudden deaths until 21 years of age. Fatal ventricular arrhythmias are usual common pathways in such tragic events, and underlying etiologies include cardiac ion channelopathies in majority of cases. We present a case of aborted sudden cardiac death in field, resuscitated successfully, and a clinical event in the pediatric emergency department that led to the diagnosis of the underlying rare condition.
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http://dx.doi.org/10.1097/PEC.0b013e318216b30c | DOI Listing |
Hypertrophic cardiomyopathy (HCM) is a genetic cardiac disorder associated with an increased risk of arrhythmias, heart failure, and sudden cardiac death. Current imaging and clinical markers are not fully sufficient in accurate diagnosis and patient risk stratification. Although known cardiac biomarkers in blood are used, they lack specificity for HCM and primarily stratify for death due to heart failure in overt cases.
View Article and Find Full Text PDFKardiol Pol
January 2025
1st Department of Cardiology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.
Eur J Pharmacol
December 2024
School of Pharmaceutical Science, Sun Yat-sen University, Guangzhou 510006, China. Electronic address:
Stroke is a serious condition with sudden onset, high severity, and significant rates of mortality and disability, ranking as the second leading cause of death globally at 11.6%. Hemorrhagic stroke, characterized by non-traumatic rupture of cerebral vessels, can cause secondary brain injury such as neurotoxicity, inflammation, reactive oxygen species, and blood-brain barrier (BBB) damage.
View Article and Find Full Text PDFToxicol Appl Pharmacol
December 2024
Department of Surgery, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, the Netherlands. Electronic address:
Introduction: Accurate staging of malignancies often requires comprehensive evaluation of lymph nodes. However, finding these lymph nodes during oncological surgery is a daunting and time-consuming task, which increases the risk of missed lymph nodes and complications. Near-infrared (NIR) fluorescence imaging with the experimental fluorescent contrast agent PanLN800(-Forte) could provide real-time identification of lymph nodes and may solve this longstanding problem.
View Article and Find Full Text PDFRev Cardiovasc Med
December 2024
Department of Emergency, The Eighth Affiliated Hospital of Sun Yat-sen University, 518033 Shenzhen, Guangdong, China.
Myocarditis, a life-threatening disease that can result in cardiac arrest and sudden cardiac death, has garnered significant attention in recent years. This review provides a comprehensive overview of the management of myocarditis-related sudden cardiac death, encompassing its pathology, diagnostic methods, therapeutic strategies, preventive measures, prognostic factors, and risk stratification. Additionally, the review highlights current challenges and future directions in this field.
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