Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/cid/cir171 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Dual Drug-Loaded Coaxial Nanofiber Dressings for the Treatment of Diabetic Foot Ulcer.
Int J Nanomedicine
June 2024
Advanced Diagnostics and Therapeutics Technologies Institute, Health Sector, King Abdulaziz City for Science and Technology (KACST), Riyadh, 11442, Saudi Arabia.
Introduction: Diabetes mellitus is frequently associated with foot ulcers, which pose significant health risks and complications. Impaired wound healing in diabetic patients is attributed to multiple factors, including hyperglycemia, neuropathy, chronic inflammation, oxidative damage, and decreased vascularization.
Rationale: To address these challenges, this project aims to develop bioactive, fast-dissolving nanofiber dressings composed of polyvinylpyrrolidone loaded with a combination of an antibiotic (moxifloxacin or fusidic acid) and anti-inflammatory drug (pirfenidone) using electrospinning technique to prevent the bacterial growth, reduce inflammation, and expedite wound healing in diabetic wounds.
The origin of sequence type 72 community-associated methicillin-resistant Staphylococcus aureus (MRSA) and fusidic acid (FA) resistant sequence type 5 MRSA: Analysis of FA resistance and spa type in a single center in South Korea.
J Infect Chemother
April 2024
Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea; Center for Antimicrobial Resistance and Microbial Genetics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. Electronic address:
Introduction: We investigated the prevalence of fusidic acid (FA) resistance in MSSA and MRSA stratified by sequence (ST) and spa types, and determined the prevalence of FA resistance mechanisms.
Methods: From August 2014 to April 2020, S. aureus blood isolates were collected in Asan Medical Center, Seoul, South Korea.
Co-carriage of and among children younger than 2 years of age in a rural population in Pakistan.
Clin Epidemiol Glob Health
January 2023
Department of Pediatric and Child Health, Aga Khan University, Karachi, Pakistan.
Objectives: and are common colonizers of the human nasopharynx. In this study, we describe nasopharyngeal carriage and evaluate its association with carriage post-10-valent pneumococcal conjugate vaccine (PCV10) introduction in Pakistan.
Methods: A serial cross-sectional study was undertaken from 2014 to 2018, children <2 years were randomly selected, and nasopharyngeal swabs were collected using standard WHO guidelines.
Ligand and structure-based approaches for the exploration of structure-activity relationships of fusidic acid derivatives as antibacterial agents.
Front Chem
January 2023
School of Biotechnology and Health Sciences, Wuyi University, Jiangmen, China.
Fusidic acid () has been widely applied in the clinical prevention and treatment of bacterial infections. Nonetheless, its clinical application has been limited due to its narrow antimicrobial spectrum and some side effects. Therefore, it is necessary to explore the structure-activity relationships of derivatives as antibacterial agents to develop novel ones possessing a broad antimicrobial spectrum.
View Article and Find Full Text PDFEpidemiology and antimicrobial resistance of staphylococci other than from domestic animals and livestock in Africa: a systematic review.
Front Vet Sci
December 2022
Division of Medical Microbiology and Immunology, Stellenbosch University, Stellenbosch, South Africa.
Introduction: Staphylococci other than Staphylococcus aureus (SOSA) in animals are becoming more pathogenic and antibiotic resistant and can potentially disseminate to humans. However, there is little synthesized information regarding SOSA from animals in Africa. This systematic review provides a comprehensive overview of the epidemiology and antimicrobial resistance of SOSA in companion animals (pets) and livestock in Africa.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!