Food-dependent exercise-induced anaphylaxis (FDEIA) is a rare syndrome, with symptoms caused by both ingestion of food allergen and physical exercise. The main purpose of this paper is to present current knowledge about FDEIA, focus on therapeutic possibilities, as well as to call attention to this uncommon and potentially life-threatening disease. The authors critically reviewed the data from available publications, including recent observations regarding pathomechanism, clinical history, severity-based classification of anaphylaxis symptoms, diagnostics and treatment options, including pharmacological prophylaxis.
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Clin Exp Allergy
December 2024
Department of Dermatology and Allergy Centre, Odense Research Center for Anaphylaxis (ORCA), Odense University Hospital, Odense C, Denmark.
Front Allergy
October 2024
Allergy and Immunology Division, Department of Medicine, Hamad Medical Corporation, Doha, Qatar.
Food-dependent exercise-induced anaphylaxis (FDEIA) is a rare and complex clinical condition in which allergic reactions are triggered by specific foods combined with physical activity, even though the food allergen and exercise are tolerated individually. Wheat is the most common culprit food leading to wheat dependent exercise induced anaphylaxis (WDEIA). Management of FDEIA is challenging due to the unpredictability of attacks and the lack of approved prophylactic medications.
View Article and Find Full Text PDFCurr Allergy Asthma Rep
November 2024
Department of Pediatrics, Division of Pulmonology, Allergy & Immunology, University of Tennessee Health Science Center, LeBonheur Children's Hospital, 51 N. Dunlap Street, Suite 400, Memphis, TN, 38105, USA.
J Allergy Clin Immunol Glob
November 2024
Department of Immunology, Beaumont Hospital, Dublin, Ireland.
Asia Pac Allergy
August 2024
Department of Allergy, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
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