Primary fourth ventricle meningiomas are extremely rare, and they are defined as meningiomas arising from the choroid plexus and lying strictly within the fourth ventricle. In this report we present a 61-year-old man with progressive worsening vertigo and gait disturbance, and new onset of diplopia. Neurological examination revealed bilateral abducens nerve paralysis, horizontal nystagmus, and gait disturbance with truncal ataxia. Neuroimaging revealed a mass lesion in the fourth ventricle with brain stem compression, and obstructive hydrocephalus. The patient was operated in the prone position with suboccipital craniotomy and splitting the lower vermis. Total resection of the tumor was achieved with no intra- or post-operative complications. Histopathologic examination revealed fibroblastic type meningioma (WHO grade I).
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http://dx.doi.org/10.5137/1019-5149.JTN.2869-09.0 | DOI Listing |
J Neuroimaging
December 2024
Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Background And Purpose: In idiopathic normal pressure hydrocephalus (iNPH) patients, cerebrospinal fluid (CSF) flow is typically evaluated with a cardiac-gated two-dimensional (2D) phase-contrast (PC) MRI through the cerebral aqueduct. This approach is limited by the evaluation of a single location and does not account for respiration effects on flow. In this study, we quantified the cardiac and respiratory contributions to CSF movement at multiple intracranial locations using a real-time 2D PC-MRI and evaluated the diagnostic value of CSF dynamics biomarkers in classifying iNPH patients.
View Article and Find Full Text PDFFront Med (Lausanne)
December 2024
Medical College of Soochow University, Suzhou, Jiangsu, China.
Background: The co-occurrence of pulmonary hypertension (PH) in patients with pulmonary fibrosis (PF) is linked to a more unfavorable prognosis and increased mortality compared to PF cases without PH. Early intervention and comprehensive management are pivotal for improving survival outcomes. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a protein essential in cholesterol metabolism.
View Article and Find Full Text PDFRadiol Case Rep
February 2025
Department of Pathology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Sawangi (Meghe), Wardha, Maharashtra, India, 442001.
The occurrence of isolated bilateral hippocampus infarct is extremely rare and is thought to be associated with a number of etiologies, including ischemia, infection, paraneoplastic syndromes, seizures, drug addiction, etc. The presented manuscript depicts a case of a 28-year-old male patient who has been a chronic alcoholic for the past 4 years and, on imaging, was found to have a bilateral hippocampal infarct in isolation. Also, the manuscript presents the appearance of the magnetic resonance imaging (MRI) of Bochdalek's flower basket, which is an anatomical variant of the choroid plexus in the fourth ventricle.
View Article and Find Full Text PDFFluids Barriers CNS
December 2024
C.J. Gorter MRI Center, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
Background: Cerebrospinal fluid (CSF) motion and pulsatility has been proposed to play a crucial role in clearing brain waste. Although its driving forces remain debated, increasing evidence suggests that large amplitude vasomotion drives such CSF fluctuations. Recently, a fast blood-oxygen-level-dependent (BOLD) fMRI sequence was used to measure the coupling between CSF fluctuations and low-frequency hemodynamic oscillations in the human cortex.
View Article and Find Full Text PDFBMC Pediatr
December 2024
Pediatric Intensive Care Unit, Guangzhou Women and Children's Medical Center (Guangzhou Medical University), Guangzhou, Guangdong, 510030, China.
Background And Objective: Microsurgical resection of tumor is an important treatment for children with fourth ventricular tumors. There is a lack of data describing risk factors for postoperative extubation failure (EF) in these children. We aimed to identify risk factors for EF in children with fourth ventricular tumors and to determine the association between EF and clinical outcomes.
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