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Explainable artificial intelligence with UNet based segmentation and Bayesian machine learning for classification of brain tumors using MRI images.
Sci Rep
January 2025
Department of Electronics, Information and Communication Engineering, Kangwon National University, Samcheok, Republic of Korea.
Detecting brain tumours (BT) early improves treatment possibilities and increases patient survival rates. Magnetic resonance imaging (MRI) scanning offers more comprehensive information, such as better contrast and clarity, than any alternative scanning process. Manually separating BTs from several MRI images gathered in medical practice for cancer analysis is challenging and time-consuming.
View Article and Find Full Text PDFDoes a distal radial fracture lead to osteoarthritis? Re-examining the evidence for early treatment.
J Hand Surg Eur Vol
January 2025
University Hospital Southampton, Southampton, UK.
There are many good reasons to improve the anatomy of a distal radius fracture, such as early return to function and avoidance of sigmoid notch incongruity or ulnocarpal impaction. It is often feared by patients, and portrayed by some authors of scientific articles and medicolegal reports, that a fracture of the distal radius has a propensity to cause symptomatic osteoarthritis. This article examines some of the current evidence and shares the authors' experience.
View Article and Find Full Text PDFKirners deformity - a systematic review and surgery recommendations.
Arch Orthop Trauma Surg
January 2025
Abteilung für Plastische und Handchirurgie UniversitätsCentrum für Orthopädie, Unfall- & Plastische Chirurgie, Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden, Dresden, Germany.
Background: Kirner deformity is a rare anomaly of the little finger in adolescents, characterized by a deformity of the distal phalanx and a radiologically L-shaped epiphysis, along with palmar and radial angulation of the distal phalanx. Due to the rarity of these pathological findings, there are no systematic literature reviews available. This work serves as an overview of the clinical presentation, frequency and age distributions, as well as possible conservative and surgical treatment options.
View Article and Find Full Text PDFEnhanced Accumulation and Penetration of Magnetic Nanoclusters in Tumors Using an 8-Magnet Halbach Array Leads to Improved Cancer Treatment.
ACS Nano
January 2025
Department of Bioengineering, University of Pennsylvania, 210 S. 33rd Street, 435 Skirkanich Hall, Philadelphia, Pennsylvania 19104, United States.
Nanoparticles have gained attention as drug delivery vehicles for cancer treatment, but often struggle with poor tumor accumulation and penetration. Single external magnets can enhance magnetic nanoparticle delivery but are limited to superficial tumors due to the rapid decline in the magnetic field strength with distance. We previously showed that a 2-magnet device could extend targeting to greater tissue depths.
View Article and Find Full Text PDFThe usability of a virtual reality augmented training program to teach goniometry to occupational therapy students.
BMC Med Educ
January 2025
Institute of Health and Wellbeing, Federation University, Ballarat, Australia.
Background: Training occupational therapy students in manual skills such as goniometry typically requires intensive one on one student teacher interactions and repetitive practice to ensure competency. There is evidence that immersive virtual reality (IVR) supported embodied learning can improve confidence and performance of skills. Embodied learning refers to learner's experience of viewing a simulated body and its properties as if they were the learner's own biological body.
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