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Current androgen receptor antagonists under investigation for resistant prostate cancer: progress and challenges.
Expert Rev Anticancer Ther
March 2025
Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Introduction: Prostate cancer represents a significant oncological challenge, with its natural history predominantly driven by androgen receptor (AR) signaling. The pivotal role of this pathway underscores the rationale for targeting AR activity in therapeutic strategies. However, the development of resistance mechanisms has highlighted the need for advanced therapies to address the complexity of the castration-resistant status.
View Article and Find Full Text PDFKnowledge, attitude and practices of Saudi pharmacists regarding CVD risk factors and associated barriers.
Pak J Pharm Sci
March 2025
Department of Clinical Pharmacy, College of Pharmacy, King Khalid University, Alfaraa, Abha, Saudi Arabia.
Risk assessment for cardiovascular diseases (CVD) is fundamental to prevention, enabling early intervention when risks are recognized. This cross-sectional study focuses on evaluating the knowledge, attitude, practices and perceived barriers of Saudi pharmacists regarding CVD risk factors. A self-administered survey was employed to collect the responses from the participants over a period of four months.
View Article and Find Full Text PDFLeveraging artificial intelligence for inclusive maternity care: Enhancing access for mothers with disabilities in Africa.
Womens Health (Lond)
March 2025
Department of Public Health Medicine, University of KwaZulu-Natal, Durban, South Africa.
Women with disabilities face significant barriers in accessing maternal healthcare, which increases their risk of adverse pregnancy outcomes, particularly in Africa, where resources are limited. Artificial intelligence (AI) presents a unique opportunity to improve inclusivity and accessibility to antenatal care, skilled birth attendance and postnatal care for these women. This paper explores the potential of AI to address the socio-economic, physical, and institutional barriers that limit the utilisation of maternal healthcare services by women with disabilities.
View Article and Find Full Text PDFFactors associated with undernutrition among pregnant women in Chiro district, eastern Ethiopia.
Womens Health (Lond)
March 2025
Department of Biology, College of Natural and Computational Science, Oda Bultum University, Chiro, Ethiopia.
Background: Undernutrition denotes inadequate intake of energy and nutrients to meet one's optimal needs. Pregnant women are at an increased risk of undernutrition due to the added nutritional demand for fetal growth and development. Updated evidence is important for monitoring progress and informing healthcare decisions.
View Article and Find Full Text PDFNetwork dynamics of social influence on e-cigarette use among an ethnically diverse adolescent cohort.
Nicotine Tob Res
March 2025
Department of Population and Public Health Sciences, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States.
Introduction: The objective of this study was to examine the mechanisms of social influence driving e-cigarette use in adolescent social networks and differentiate between the effects of exposure to friend behavior and social norms on individual use.
Methods: Surveys on health behaviors and friendship networks from nine high schools in Southern California (N = 2,245; 48% Hispanic) were collected at three time points from Spring 2021 of grade 9, Fall 2021, and Spring 2022 of grade 10. Stochastic actor-oriented models for the co-evolution of social networks and behavior dynamics tested for friendship network social influences on e-cigarette use.
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