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Rare histopathological diagnosis of malakoplakia and Rosai‑Dorfman disease in the same uterus mimicking malignancy: A case report.
Exp Ther Med
February 2025
Department of Histopathology, Specialty Hospital, Amman 11194, Jordan.
In the present case, a 66-year-old woman presented to the Specialty Hospital (Amman, Jordan) with recurrent post-menopausal bleeding. A pelvic ultrasound scan showed an abnormal endometrial thickness of 8 mm and no adnexal masses. An endometrial biopsy revealed abundant foamy histiocyte infiltration features suggestive of xanthogranulomatous endometritis.
View Article and Find Full Text PDFCo-existence of autoimmune polyglandular syndrome type 3b and undifferentiated connective tissue disease with subacute combined degeneration of spinal cord in children: a case report and literature review.
BMC Pediatr
December 2024
Department of Pediatrics, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Background: The clinical manifestations of subacute combined degeneration of spinal cord (SCD) in children are complex and vary greatly. Notably, some SCD patients may be complicated with autoimmune diseases, leading to high early misdiagnosis and missed diagnosis rates.
Case Presentation: In this study, a case involving an adolescent female with repetitive severe anemia, multiple joint swelling and pain in the left limbs, and paralysis of the bilateral lower limbs with serum vitamin B12 deficiency, polyglandular involvement, and various positive auto-antibodies (anti‑intrinsic factor antibody, anti‑parietal cell antibody, thyroid peroxidase antibody, thyroid globulin antibody and perinuclear anti‑neutrophil cytoplasmic antibody) is reported.
Co-existing Ankylosing Spondylitis and Rheumatoid Arthritis in a Patient Undergoing Total Knee Arthroplasty Under Peripheral Nerve Blocks.
J Orthop Case Rep
October 2024
Department of Arthroplasty, Sancheti Institute for Orthopaedics and Rehabilitation, Pune, Maharashtra, India.
Article Synopsis
- Simultaneous symptoms in conditions like Ankylosing Spondylitis (AS) and Rheumatoid Arthritis (RA) can lead to misdiagnosis and delayed treatment, highlighting the importance of accurate early diagnosis.
- A case involving a 63-year-old man with AS developing knee arthritis revealed the coexistence of RA, necessitating total knee replacement surgery after multiple joint replacements.
- The challenges in diagnosing these overlapping conditions underline the need for heightened awareness among healthcare providers to prevent costly diagnostic errors.
MRI findings in autoimmune encephalitis.
Rev Neurol (Paris)
November 2024
Charité - Universitätsmedizin Berlin, Department of Neurology and Experimental Neurology, Berlin, Germany; Humboldt-Universität zu Berlin, Berlin School of Mind and Brain, Berlin, Germany; Charité - Universitätsmedizin Berlin, Einstein Center for Neurosciences Berlin, Berlin, Germany. Electronic address:
Article Synopsis
- In NMDA receptor encephalitis, most patients have normal MRIs during acute episodes, but subtle lesions can occur; these lesions may signal overlaps with conditions like multiple sclerosis or neuromyelitis optica.
- Other types, such as limbic encephalitis related to LGI1, CASPR2, and GAD antibodies, show specific hyperintensities in the medial temporal lobe on MRI, while GABA receptor encephalitides present different patterns of lesions, underscoring the importance of MRI in diagnosing autoimmune encephalitis and differentiating it from other disorders.
A Homozygous Variant in NAA60 Is Associated with Primary Familial Brain Calcification.
Mov Disord
December 2024
Department of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Background: Primary familial brain calcification (PFBC) is a monogenic disorder characterized by bilateral calcifications in the brain. The genetic basis remains unknown in over half of the PFBC patients, indicating the existence of additional novel causative genes. NAA60 was a recently reported novel causative gene for PFBC.
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