AI Article Synopsis
- Accurate radiological staging is crucial for effectively treating small-cell lung cancer (SCLC), helping to identify patients with limited stage disease for curative options and sparing others with advanced disease from unnecessary treatment.
- [(18)F] flurodeoxy-D-glucose (FDG) positron emission tomography (PET) shows promise for this purpose, but there's limited evidence backing its routine use in SCLC staging.
- Current research suggests that the role of FDG-PET in making treatment decisions is still unclear, with preliminary findings indicating it may have potential as a prognostic biomarker and in planning radiation therapy.
Article Abstract
Accurate radiological staging of small-cell lung cancer (SCLC) is of paramount importance in selection of individual patients with limited stage disease for potentially curative treatment while avoiding toxic treatment in those with distant metastatic disease. [(18)F] flurodeoxy-D-glucose (FDG) positron emission tomography (PET) is an attractive tool for this purpose but there is limited evidence to support its use in the routine staging of SCLC. Whether therapeutic decisions based on FDG-PET imaging should be made remains uncertain. There is only preliminary evidence for use of FDG-PET as a prognostic biomarker, in the assessment of response to treatment and delineation of disease in conformal radiation planning.
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| http://dx.doi.org/10.1016/j.lungcan.2011.03.013 | DOI Listing |
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