Acute pancreatitis is often complicated by acute renal failure, either isolated or part of multiple organ failure. Preexisting chronic kidney disease worsens the prognosis, especially when the pancreatitis is severe and/or other major comorbidities are present. In case of acute-on-chronic renal failure secondary to acute pancreatitis, an early application of renal replacement therapy has improved the prognosis of patients included in the present clinical study.
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