In the cation of the title compound, C(7)H(8)N(5) (+)·Cl(-)·H(2)O, the mean planes of the pyridine and 1,2,4-triazole rings form a dihedral angle of 2.3 (1)°. The N atom of the amino group adopts a trigonal-pyramidal configuration. The N atom of the pyridine ring is protonated, forming a chloride salt. In the crystal, inter-molecular N-H⋯O, N-H⋯N, N-H⋯Cl and O-H⋯Cl hydrogen bonds link the cations, anions and water mol-ecules into layers parallel to the (1, 0, ) plane.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051743 | PMC |
| http://dx.doi.org/10.1107/S1600536811002406 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effects of acute hydration changes on cardiovascular magnetic resonance native T1 and T2 mapping.
Int J Cardiovasc Imaging
December 2024
Department of Cardiology, The Heart Centre, Copenhagen University Hospital - Rigshospitalet, Inge Lehmanns Vej 7, Copenhagen, 2100, Denmark.
Changes in hydration status may affect myocardial native T1 and T2 values and influence the clinical interpretation. We aimed to assess the impact of acute preload augmentation on native T1 and T2. Cardiovascular magnetic resonance (CMR) native T1 and T2 mapping were performed twice on the same day in 20 healthy participants before and after an acute preload augmentation by a 2-liter intravenous infusion of isotonic sodium chloride (0.
View Article and Find Full Text PDFChloride reported missing from brain and extracellular matrix is a suspect.
J Physiol
December 2024
Department of Neuroscience and Physiology, NYU Grossman School of Medicine, New York, NY, USA.
Application of Strontium Chloride Hexahydrate to Synthesize Strontium-Substituted Carbonate Apatite as a pH-Sensitive, Biologically Safe, and Highly Efficient siRNA Nanocarrier.
ACS Appl Bio Mater
December 2024
Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, 47500 Subang Jaya, Selangor, Malaysia.
Naked siRNAs are sensitive to enzymatic degradation, phagocytic entrapment, quick renal excretion, membrane impermeability, endosomal escape, and off-target effects. Designing a safe and efficient nanocarrier for siRNA delivery to the target site without toxicity remains a significant hurdle in gene therapy. CA is a unique derivative of hydroxyapatite and a highly pH-sensitive nanocarrier with strong particle aggregation and a high polydispersity index.
View Article and Find Full Text PDFEffects of Hydrolysed Poultry Byproduct Meal on Metabolic, Inflammatory and Oxidative Parameters in Cats.
J Anim Physiol Anim Nutr (Berl)
December 2024
Department of Veterinary Clinic and Surgery, School of Agricultural and Veterinary Sciences (FCAV), São Paulo State University-UNESP, Jaboticabal, Brazil.
Hydrolysed proteins are of interest owing to their potential effects on metabolic and physiological responses, low allergenicity and high digestibility. This study aimed to evaluate the use of hydrolysed poultry byproduct meal (HPM) as a replacement for conventional poultry byproduct meal (PBM) as a protein source and to study its effects on serum cytokines, angiotensin-converting enzyme (ACE) activity, serum antioxidant parameters, blood pressure, and urinary parameters in cats. The replacement of PBM with HPM was evaluated using five formulations with similar chemical compositions: control (PBM as the sole protein source) and the inclusion of 5%, 10%, 20%, and 30% HPM (on an as-fed basis).
View Article and Find Full Text PDFAchieving over 20% Efficiency in Laminated HTM-Free Carbon Electrode Perovskite Solar Cells through In Situ Interface Reconstruction.
Angew Chem Int Ed Engl
December 2024
Shanghai Institute of Technology, School of Chemical and Environmental Engineering, CHINA.
Laminating a free-standing carbon electrode film onto perovskite film is a promising method for fabricating HTM (hole transport material)-free carbon electrode perovskite solar cells (c-PSCs), offering more flexibility by decoupling the processes of carbon electrode and perovskite layer formation. However, the power conversion efficiency (PCE) of laminated HTM-free c-PSCs (<16.5%) remains lower compared to c-PSCs with printed carbon pastes (>20%), primarily due to poor interfacial contact between the perovskite and carbon layers.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!