The mean planes of the two benzene rings in the title compound, C(17)H(16)FNO, are twisted slightly, making a dihedral angle of 7.8 (1)°. The prop-2-en-1-one group is also twisted slightly with a C-C-C-O torsion angle of -11.6 (3)°. In the crystal, weak inter-molecular C-H⋯O inter-actions link pairs of mol-ecules, forming centrosymmetric dimers.
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http://dx.doi.org/10.1107/S1600536811000377 | DOI Listing |
Acta Crystallogr E Crystallogr Commun
January 2025
Department of Biotechnology SRM Institute of Science and Technology, Kattankulathur Campus Chengalpattu Tamil Nadu - 603203 India.
In the crystal structure of the title chalcone derivative, CHNO, the mol-ecule adopts an s- conformation with respect to the C=O and C=C bonds. The tri-phenyl-amine moiety has a propeller-type shape, with dihedral angles between the mean planes of pairs of phenyl rings of 72.1 (6), 69.
View Article and Find Full Text PDFActa Crystallogr E Crystallogr Commun
September 2022
Department of Chemical and Material Engineering, Chaohu College, Chaohu, People's Republic of China.
J Biomol Struct Dyn
July 2023
Department of Chemistry, Tulane University, New Orleans, Los Angeles, USA.
Infection by the human immunodeficiency virus still represents a continuous serious concern and a global threat to human health. Due to the appearance of multi-resistant virus strains and the serious adverse side effects of the antiretroviral therapy administered, there is an urgent need for the development of new treatment agents that are more active, less toxic, and with increased tolerability to mutations. Quinoxaline derivatives are a class of heterocyclic compounds with a wide range of organic and remedial applications.
View Article and Find Full Text PDFJ Biomol Struct Dyn
April 2022
Laboratoire de Chimie Organique Hétérocyclique, Centre de Recherche des Sciences des Médicaments, Pôle de Compétences Pharmacochimie, URAC 21, Faculté des Sciences, Université Mohammed V Rabat, Rabat, Morocco.
Two new compounds namely, ethyl (2E)-3-(dimethylamino)-2-(3-methoxyquinoxalin-2-yl)propen-2-enoate () and ethyl 2-(3-oxo-4-(prop-2-yn-1-yl)-3,4-dihydroquinoxalin-2-yl)-3-phenylpropanoate () have been synthesized from ethyl 2-(oxo-3,4-dihydroquinoxalin-2-yl) acetate (). The compounds were characterized using NMR (H and C), Fourier transform infrared and confirmed by single crystal X-ray diffraction studies. The quinoxaline portion of is almost planar with the substituent containing the dimethylamino and carboxyethyl groups rotated well out of its mean plane.
View Article and Find Full Text PDFActa Crystallogr E Crystallogr Commun
September 2018
Department of Chemistry, Cauvery Institute of Technology, Mandya 571 402, Karnataka, India.
The mol-ecular structure of the title compound, CHClOS, consists of a 2,5-di-chloro-thio-phene ring and a 2,4-di-chloro-phenyl ring linked a prop-2-en-1-one spacer. The dihedral angle between the 2,5-di-chloro-thio-phene ring and the 2,4-di-chloro-phenyl ring is 12.24 (15)°.
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