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Methyl 2-(1H-indole-3-carboxamido)-acetate. | LitMetric

Methyl 2-(1H-indole-3-carboxamido)-acetate.

Acta Crystallogr Sect E Struct Rep Online

Department of Chemistry, Jinan University, Guangzhou, Guangdong 510632, People's Republic of China.

Published: February 2011

The title compound, C(12)H(12)N(2)O(3), was synthesized by condensation of methyl amino-acetate with 3-trichloro-acetyl-indole. In the crystal, inter-molecular N-H⋯O hydrogen bonds link the mol-ecules into chains parallel to the b axis. The chains are further connected into a three-dimensional network by N-H⋯O hydrogen bonds involving the indole N atom. In the molecule, the indole skeleton is nearly planar [maximum deviation = 0.012 (1) Å] and the mean plane of the amido group is twisted from the mean plane of indole ring by 17.2 (1)°.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052031PMC
http://dx.doi.org/10.1107/S1600536811006660DOI Listing

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