Milk somatic cell count is an indicator trait for mastitis resistance. Genetic parameters for somatic cell score in the Portuguese Holstein-Friesian population were estimated by modeling the pattern of genetic correlation over the first 3 lactations (days in milk) with a random regression model. Data records from the first 3 lactations were from the national database of the Portuguese Holstein Association herds. Heritability estimates ranged from 0.05 at the beginning of the lactation for the 3 lactations, to 0.07 at the end of the lactation period for the first and third lactations, to 0.09 for the second lactation. This increase in the heritability values was due to an increase in the genetic variance and a decrease in the residual variances. Genetic correlations evaluated for monthly time points were high (0.65 to 0.99) for all 3 lactations, whereas phenotypic correlations were much less than the genetic correlations (0.13 to 0.62).
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