Thoracic aorta pseudoaneurysm with hemopericardium: unusual presentation of warfarin overdose.

J Occup Med Toxicol

Department of Medicine, Changhua Christian Hospital, 135 Nan-Siau Street, Changhua city, 500 Taiwan.

Published: April 2011

There have been few case reports which discuss a relationship between warfarin overdose and aortic pseudoaneurysm leakage. We report the case of a female receiving warfarin who presented with dsypnea. Her international normalized ratio was > 10. Chest radiograph revealed cardiomegaly, and chest computed tomography (CT) showed a bulging pouch-like lesion below the aortic arch greater than 6x6 cm in size and a fluid collection suggesting blood in the pericardium. Thoracic endovascular aneurysm repair (TEVAR) was successfully performed by a cardiovascular surgeon. Aortic pseudoaneurysm formation and leakage may be considered as a rare complication in patients receiving warfarin therapy. Further study regarding warfarin use and the incidence of pseudoaneurysm leakage is needed.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114796PMC
http://dx.doi.org/10.1186/1745-6673-6-12DOI Listing

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