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Identification of Ancylostoma caninum in Domestic Dogs from Ecuador via Various Techniques.
Med Sci Monit
January 2025
Institute of Invertebrates, Fundación Miguel Lillo, San Miguel de Tucumán, Argentina.
BACKGROUND Ancylostoma caninum is a soil-borne, soil-transmitted helminth with infective larvae and produces cutaneous larva migrans in humans. The objective of this study was to confirm the presence of A. caninum in domestic dogs from the urban-marginal and rural sectors of the Ecuadorian coast through morphometry, culture, and molecular techniques.
View Article and Find Full Text PDFRelative effectiveness of the second booster COVID-19 vaccines against laboratory confirmed SARS-CoV-2 infection in healthcare workers: VEBIS HCW VE cohort study (1 October 2022-2 May 2023).
Vaccine
December 2024
Department of Epidemiology, Epiconcept, Paris, France.
Introduction: Repeated COVID-19 booster vaccination was recommended in healthcare workers (HCWs) to maintain protection. We measured the relative vaccine effectiveness (rVE) of the second booster dose of COVID-19 vaccine compared to the first booster, against laboratory-confirmed SARS-CoV-2 infection in HCWs.
Methods: In a prospective cohort study among HCWs from 12 European hospitals, we collected nasopharyngeal or saliva samples at enrolment and during weekly/fortnightly follow-up between October 2022 and May 2023.
Worldwide trends in childhood overweight and obesity over the last 20 years.
Clin Nutr ESPEN
December 2024
Department of Community Medicine and Global Health, Institute of Health and Society, University 7 of Oslo, Oslo, Norway.
Background: Child overweight and obesity is associated with an increased risk of non-communicable diseases. The present work aimed to explain the global trends of overweight in children under 5 years during the last two decades in comparison to the global nutrition targets.
Methods: We analysed secondary data from the Global Nutrition Report 2020 report for the years 2000 to 2020 from 194 countries, distributed in 23 sub-regions to examine the changes in prevalence and trends of overweight and obesity in children under five years of age.
Effect of Silibinin on Human Pancreatic Lipase Inhibition and Gut Microbiota in Healthy Volunteers: A Randomized Controlled Trial.
Int J Mol Sci
November 2024
Unidad de Investigación de Trastornos de la Alimentación, Facultad de Enfermería, Universidad Católica de Murcia, Campus de Guadalupe, Avda. de Los Jerónimos, s/n, 30107 Murcia, Spain.
Thistle () has been traditionally employed for liver protection. However, we recently identified silibinin, the main bioactive compound of thistle extract, as an in vitro pancreatic lipase inhibitor, which suggested a potential role as an anti-obesity agent. This study aimed to assess, in vivo, the efficacy, safety, and effects of silibinin on human lipase.
View Article and Find Full Text PDFSex-Dependent Gut Microbiota Features and Functional Signatures in Metabolic Disfunction-Associated Steatotic Liver Disease.
Nutrients
December 2024
Department of Nutrition, Food Sciences and Physiology and Centre for Nutrition Research, Faculty of Pharmacy and Nutrition, University of Navarra, 31008 Pamplona, Spain.
: This study investigates the gut microbiota's role in metabolic dysfunction-associated steatotic liver disease (MASLD), focusing on microbial and functional signatures and sex-based differences. : Using baseline data from 98 MASLD patients and 45 controls from the Fatty Liver in Obesity (FLiO) study, the gut microbiota was profiled with 16S gene sequencing, followed by statistical and machine learning analyses to identify disease-associated microbial signatures. : Notable alpha and beta diversity differences were observed between MASLD patients and the controls, varying by sex.
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