Objective: Analysis of perimetric deficit progression and accurate evaluation of certain factors that are associated with perimetric progression in glaucomatous patients.

Material And Methods: Cohort clinical trial that included a number of 80 eyes in 46 patients having a clear diagnosis of open angle glaucoma or ocular hypertension medically and/or surgically treated in which there have been followed both the dynamics in perimetric deficits and morpho functional parameters related closely and characteristically to the glaucomatous disease. Progression analysis was made using two different methods: manual, testing each spot's sensitivity at a time (EGS criterias were utilized) and automatic (through GPATM--Glaucoma Progression Analysis software).

Results: The study group (80 eyes) was evaluated and analyzed over a period of 63.8 months; in 27.5% we detected perimetric progression as it follows: 15 eyes by the GPA analysis and 19 eyes by the manual method. Concurrency rate between the two methods reached 87%. Associated factors with perimetric progression were: pseudoexfoliation, thin cornea, older age and cardiovascular diseases.

Conclusions: Perimetry represents an essential method for the detection of glaucomatous progression. Computerized analysis methods are extremely important and come in clinician's help.

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