AI Article Synopsis
- The author reviews V. Kh. Vasilenko's theories on the causes and development of ulcer disease, comparing them to current understanding.
- The text emphasizes ulcer disease as a systemic gastrointestinal issue, distinguishing it from secondary ulceration and highlighting the role of H. pylori along with hereditary and environmental influences.
- It also explores various factors that contribute to ulcer disease, including less understood aspects like immune responses and sanogenetic mechanisms.
Article Abstract
The author discusses the views of V. Kh. Vasilenko on etiology and pathogenesis of ulcer disease expounded in his last publications and compares them with modern concepts of the origin of this condition. The nature of ulcer disease as a systemic gastrointestinal pathology is considered with special emphasis on its difference from secondary (symptomatic) ulceration, pathogenetic significance of H. pylori infection, hereditary and environmental (non-infectious) factors. Much attention is given to the conditions facilitating the development of ulcer diseases at different combinations of internal and environmental factors including such poorly known ones as immune and sanogenetic mechanisms.
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