A racemic synthesis of the ABCD ring core of the ambiguines that preserves the tertiary alcohol has been accomplished in convergent synthesis in 10 synthetic steps, in an overall yield of 46% from commercially available 4-bromoindole and m-methylanisole.
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| http://dx.doi.org/10.1016/j.tetlet.2010.09.086 | DOI Listing |
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