Background: Following Bentall surgery, aortic graft infection can be a serious complication with high mortality rates. The recommended treatment for aortic graft infection is to explant the graft; however, because of the high risk and costs involved, this might not always be an option. We report successful treatment of a case of aortic graft infection without removal of the infected graft.
Methods: A 43-year-old man with aortic graft infection was treated by local debridement, continuous antibiotic irrigation with intermittent fast irrigation, drainage, and nutritional support in combination with systemic antibiotics.
Results: The patient was discharged 24 days after the intervention and the laboratory test values were normalized. Three years after the surgery, the patient was in good condition and showed no signs of infection.
Conclusion: The present case demonstrated that prompt debridement followed by continuous local irrigation, drainage, and nutritional support, in combination with systemic antibiotics, can be effective in the treatment of aortic graft infection. One of the most important aspects in such complicated situations is early diagnosis and optimal treatment. Our results are encouraging; however, because it was only a single case, we feel more research with a larger prospective randomized trial is warranted.
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http://dx.doi.org/10.1016/j.avsg.2010.11.016 | DOI Listing |
J Clin Invest
January 2025
Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University; State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing, China.
The pathogenesis of thoracic aortic aneurysm (TAA) in Marfan syndrome (MFS) is generally attributed to vascular smooth muscle cell (VSMC) pathologies. However, the role of immune cell-mediated inflammation remains elusive. Single-cell RNA sequencing identified a subset of CX3CR1+ macrophages mainly located in the intima in the aortic roots and ascending aortas of Fbn1C1041G/+ mice, further validated in MFS patients.
View Article and Find Full Text PDFJ Spine Surg
December 2024
Department of Neurosurgery, Geisinger Neuroscience Institute, Danville, PA, USA.
Anterior lumbar interbody fusion (ALIF) is an anterior surgical approach for interbody fusion in the lumbar spine which affords the surgeon unfettered access to the disc space and allows for release of the anterior longitudinal ligament and insertion of a large, lordotic interbody graft. Despite the benefits associated with ALIF when compared with other lumbar interbody fusion techniques, the ALIF approach is associated with a number of unique complications, and certain patient-specific criteria (e.g.
View Article and Find Full Text PDFJACC Cardiovasc Interv
January 2025
Department of Heart Failure and Transplantation, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan. Electronic address:
Eur J Vasc Endovasc Surg
January 2025
German Aortic Centre, Department of Vascular Medicine, University Heart and Vascular Centre UKE Hamburg, Hamburg, Germany.
Objective: Half of re-interventions after fenestrated and branched endovascular aortic repair (FB-EVAR) are target vessel related. Regarding bridging stent choice, existing data are controversial. This meta-analysis aimed to evaluate the performance of Advanta V12/iCAST as bridging stent in FB-EVAR.
View Article and Find Full Text PDFPancreas
January 2025
Department of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh - 160012, India.
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