AI Article Synopsis
- Bright light therapy, particularly infrared radiation, has been researched for its potential to alleviate symptoms of depression and anxiety in humans.
- In an animal study, rats were divided into groups receiving either acute or chronic exposure to infrared radiation, or a control group that was not exposed but received a placebo treatment.
- Results showed that chronic exposure to infrared radiation significantly reduced signs of depression and anxiety in the rats, suggesting potential therapeutic benefits similar to those seen with bright light therapy in humans.
Article Abstract
Background: Bright light therapy has been shown to have antidepressant and anxiolytic effects in humans.
Objective: The antidepressant and anxiolytic effects of infrared radiation were evaluated using an experimental animal model.
Methods: Rats were randomly assigned to either an acutely or chronically exposed infrared radiation group or to a nonexposed control group. Acutely exposed rats were treated with an infrared radiation machine for one session, whereas chronically exposed animals were treated with an infrared radiation for 10 sessions. Control group rats were exposed to the sound of the infrared radiation machine as a sham treatment. After infrared radiation or control exposure, rats underwent behavioral evaluation, including elevated plus maze test, light/dark box, and forced swim test.
Results: Chronic infrared radiation exposure decreased indicators of depression- and anxiety-like behavior. No significant effect on general locomotor activity was observed. The number of BrdU-positive cells in CA1 of the hippocampus was significantly increased in both acutely and chronically exposed infrared radiation groups compared with the control group.
Conclusions: These results indicate that chronic infrared radiation might produce antidepressant- and anxiolytic-like effects.
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| http://dx.doi.org/10.1016/j.brs.2010.04.001 | DOI Listing |
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