Background/aims: Although routine postoperative follow-up is generally performed for early detection of recurrences, there is no evidence that the periodic follow-up improves survival in patients with gastric cancers. This study aimed to assess the prognostic impact of cancer-related symptomatic status during postoperative followup in gastric cancer patients.
Methodology: A total of 81 gastric cancer patients, who developed recurrences after curative surgery, were retrospectively evaluated for clinicopathological findings with regard to the relationship to cancer-related symptoms at the time recurrences were diagnosed.
Results: Undifferentiated tumor type, advanced T-stage (T3/4) and peritoneal recurrence were more common in symptomatic patients groups, whereas differentiated tumor type and both locoregional and hematogenous recurrences were more common in asymptomatic patients (p = 0.02, 0.03 and 0.03, respectively). Disease-free survival showed that there were no significant differences between the asymptomatic and symptomatic patient group. However, the post-recurrence survival in patient with symptoms was significantly worse than that in those without symptoms (p < 0.01).
Conclusions: Cancer-related symptomatic status at the time recurrences are diagnosed might provide prognostic information predicting post-recurrence survival. However, we have to conclude that even intensive follow-up did not contribute to the early detection of recurrences in patients with gastric cancers.
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