The article presents the experience of the BIS monitoring in comparison with indicators of the pediatric Glasgow coma scale in 20 children with severe traumatic brain injury. Analyzed sample consists of 881 observations that contain two variables that contain high-quality sequence (a score on a scale of Glasgow in grades) and quantitative discrete values (the values of BIS). The Analysis is carried out by the nonparametric statistics with the definition of the relation between quality and quantity of ordinal traits by the rank correlation. The Spearman's coefficient rank correlation between scoring on Glasgow coma scale and the magnitude of BIS was R = 0.85 p < 0.001. Thus, the results showed that during severe traumatic brain injury in children the values of BIS have a high degree of correlation with the depth of coma on the Glasgow coma scale.
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Front Med (Lausanne)
January 2025
Department of Public Health and Forensic Sciences, and Medical Education, Faculty of Medicine, University of Porto, Porto, Portugal.
Introduction: Adverse childhood experiences (ACEs) refer to traumatic life events occurred in childhood that comprise abuse (e.g., psychological, physical, sexual), neglect (psychological and physical), indirect violence or household dysfunctions.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
January 2025
Department of Family Medicine/Supportive Care Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Background: Amputation confers disabilities upon patients and is linked to cardiometabolic morbidity and mortality. We aimed to compare the incidence of type 2 diabetes (T2DM) between individuals following amputation with those of the general population.
Methods: We performed a population-based retrospective cohort study using the Nationwide Health Insurance Service database.
Front Psychiatry
January 2025
Sociedad Española de Medicina Psicodélica (SEMPsi), Barcelona, Spain.
Background: Psychotherapy for Prolonged Grief Disorder (PGD), a condition characterized by an intense and persistent grief response, has received increased attention over the past decades. Evidence-based approaches to prevent PGD are currently scarce, and not always effective. This paper introduces a protocol for a clinical trial exploring the effectiveness of a Meaning Reconstruction psychotherapy approach (MR) assisted with ayahuasca, a traditional indigenous medicine.
View Article and Find Full Text PDFJ Neuroinflammation
January 2025
Center for Immunology and Inflammation, The Feinstein Institutes for Medical Research, Manhasset, NY, 11030, USA.
Central nervous system (CNS) injuries, such as ischemic stroke (IS), intracerebral hemorrhage (ICH) and traumatic brain injury (TBI), are a significant global burden. The complex pathophysiology of CNS injury is comprised of primary and secondary injury. Inflammatory secondary injury is incited by damage-associated molecular patterns (DAMPs) which signal a variety of resident CNS cells and infiltrating immune cells.
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