Objective: To assess the effect of the static force of a bone vibrator on the results of bone conduction (BC) threshold measurements and comfort.
Design: BC thresholds were determined for 40 participants using the standardized P-3333 headband and a leather adjustable headstrap with variable static forces (2.4, 3.4, 4.4, 5.4 N). Comfort ratings were examined using a five-point Likert scale.
Results: Mean BC thresholds were within ± 2 dB across all conditions; differences may be considered small enough to be clinically insignificant. Participants experienced significantly greater discomfort with the P-3333 versus the adjustable headstrap. The mean static force of the P-3333 varied considerably and was higher in situ than the calibration standard of 5.4 N.
Conclusions: The results suggest that future revisions of relevant international and national standards should address the use of an adjustable headstrap and a static force less than 5.4 N.
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http://dx.doi.org/10.3109/14992027.2011.568013 | DOI Listing |
Metabolomics
January 2025
Laboratory of Applied Mass Spectrometry, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
Introduction: Hemodynamic forces play a crucial role in modulating endothelial cell (EC) behavior, significantly influencing blood vessel responses. While traditional in vitro studies often explore ECs under static conditions, ECs are exposed to various hemodynamic forces in vivo. This study investigates how wall shear stress (WSS) influences EC metabolism, focusing on the interplay between WSS and key metabolic pathways.
View Article and Find Full Text PDFRespir Physiol Neurobiol
January 2025
School of Mechanical and Mechatronic Engineering, Faculty of Engineering and Information Technology, University of Technology Sydney, Sydney, NSW 2007, Australia. Electronic address:
Central and Obstructive Sleep Apnea (CSA and OSA), Chronic Obstructive Pulmonary Disease (COPD), and Obesity Hypoventilation Syndrome (OHS) disrupt breathing patterns, posing significant health risks and reducing the quality of life. Bilevel Positive Airway Pressure (BiPAP) therapy offers adjustable inhalation and exhalation pressures, potentially enhancing treatment adaptability for the above diseases. This is the first-ever study that employs Computational Fluid Dynamics (CFD) to examine the biomechanical impacts of BiPAP under four settings: Inspiratory Positive Airway Pressure (IPAP)/Expiratory Positive Airway Pressure (EPAP) of 12/8, 16/6, and 18/8 cmHO, compared to a without-BiPAP scenario of zero-gauge pressure.
View Article and Find Full Text PDFEcotoxicol Environ Saf
January 2025
State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China. Electronic address:
Honeybees, essential pollinators for maintaining biodiversity, are experiencing a sharp population decline, which has become a pressing environmental concern. Among the factors implicated in this decline, neonicotinoid pesticides, particularly those belonging to the fourth generation, have been the focus of extensive scrutiny due to their potential risks to honeybees. This study investigates the molecular basis of these risks by examining the binding interactions between Apis mellifera L.
View Article and Find Full Text PDFJ Acoust Soc Am
January 2025
College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, 310027, China.
High-efficiency electromagnetic transducers are crucial for enabling the self-sustained operation of underwater electromagnetic sound sources under power-constrained conditions as noted by Hao, Xie, and Ma [Proceedings of the 2019 Western China Acoustics Academic Conference, Guangzhou, China (November 5-9, 2019)]. This paper proposes a permanent magnet drive technology to enhance the electromechanical conversion efficiency of can-type electromagnetic transducers under low-power driving conditions. The can-type transducers consist of coils, an armature, and a cylindrical magnetic core with a central pillar, similar to the pot core proposed by Cui, Xu, Xu, and Shui [Electr.
View Article and Find Full Text PDFJ Chem Inf Model
January 2025
Department of Biochemistry, University of Oxford, Oxford OX1 3QU, U.K.
Sugars are ubiquitous in biology; they occur in all kingdoms of life. Despite their prevalence, they have often been somewhat neglected in studies of structure-dynamics-function relationships of macromolecules to which they are attached, with the exception of nucleic acids. This is largely due to the inherent difficulties of not only studying the conformational dynamics of sugars using experimental methods but indeed also resolving their static structures.
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