Fifty patients with stable angina who had undergone elective coronary angioplasty with stenting were examined. Myocardial microlesions diagnosed from the elevated levels of troponin (Tn) I and creatine phosphate kinase MB (CPK-MB) were detected in 48-54% of the patients; however, the content of Tn I exceeded the high reference level only in 18%. Tn I is a more specific method than CPK-MB in detecting myocardial microlesions during intracoronary intervention. The signs of myocardial microlesions were most commonly detected during intervention into the arteries with types B and C stenoses in case of complicated or technically difficult stent implantation.
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Pharmacol Ther
July 2024
Université Paris Cité, Inserm, Physiopathologie et Épidémiologie des Maladies Respiratoires, F-75018 Paris, France. Electronic address:
Infect Immun
January 2018
Department of Microbiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
(the pneumococcus) is the leading cause of community-acquired pneumonia and is now recognized to be a direct contributor to adverse acute cardiac events. During invasive pneumococcal disease, can gain access to the myocardium, kill cardiomyocytes, and form bacterium-filled "microlesions" causing considerable acute and long-lasting cardiac damage. While the molecular mechanisms responsible for bacterial translocation into the heart have been elucidated, the initial interactions of heart-invaded with cardiomyocytes remain unclear.
View Article and Find Full Text PDFPLoS Pathog
August 2017
Department of Microbiology, The University of Alabama at Birmingham, Birmingham, AL, United States of America.
For over 130 years, invasive pneumococcal disease has been associated with the presence of extracellular planktonic pneumococci, i.e. diplococci or short chains in affected tissues.
View Article and Find Full Text PDFAIP Conf Proc
March 2017
Department of Radiology, University of Michigan Medical Center, Ann Arbor, MI.
Intermittent high intensity ultrasound pulses with circulating contrast agent microbubbles can induce scattered microlesions of potential value for myocardial reduction therapy. This paper presents an setup imitating the treatment for monitoring development. A preclinical imaging system with a single element transducer, synchronization and receive-only imaging transducer array has been implemented on a research platform.
View Article and Find Full Text PDFMedicine (Baltimore)
June 2017
Department of Medicine, Artificial Cardiac Stimulation Division, Hospital e Clínica São Gonçalo, São Gonçalo, RJ Department of Medicine, Anesthesiology Division, Hospital e Clínica São Gonçalo, São Gonçalo, RJ, Brazil Department of Cardiology, Shanghai First People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Introduction: The standard treatment of sinus node dysfunction (SND) is the pacemaker implantation, and the ideal methodology for the management of atrial fibrillation (AF) is rhythm control, but this is sometimes very hard to accomplish. For such actions, complete isolation of all pulmonary veins (PVI) is currently widely accepted as the best endpoint.
Case Presentation: In this case, we report a female patient, 81 years old, with controlled hypertension, without coronary artery disease, bearer of bilateral knee replacement, and dual chamber pacemaker implanted 1.
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