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Brugada Syndrome: Focus for the General Pediatrician.
Children (Basel)
February 2024
Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", 34127 Trieste, Italy.
Brugada Syndrome is an "inherited" channelopathy characterized by a predisposition to syncope and sudden death. It typically presents in young adults but is also known to affect the pediatric population, even if the prevalence is low compared to the adult population. The diagnostic ECG pattern shows coved-type ST-segment elevation in the right precordial leads, occurring spontaneously or after provocative drug tests with IV administration of Class I antiarrhythmic drugs.
View Article and Find Full Text PDFIntroduction: Patient-reported outcomes (PROs) are health reports that come directly from the patients themselves and represented the experience and insights of the patient's perspective on the impact of the intervention. PROs were increasingly emphasised in acupuncture randomised controlled trials (RCTs). However, the reporting quality of PROs in acupuncture RCTs has not been investigated to date.
View Article and Find Full Text PDF"Inherited cardiovascular disease mindset" can identify concealed inherited conditions at cardio-oncology evaluation: An opportunistic screening.
Int J Cardiol
April 2024
Cardiology Department, La Paz University Hospital, IdiPAZ Research Institute, Madrid, Spain.
Introduction: Baseline cardiovascular (CV) risk stratification is recommended in all cancer patients. Integrating all clinical information (personal/family history, ECG and echocardiogram) can properly identify high-risk patients. We aimed to evaluate the concealed inherited CV conditions detected in mandatory CV screening performed at a Cardio-Oncology Unit.
View Article and Find Full Text PDFIdentification of concealed cardiomyopathy using next-generation sequencing-based genetic testing in Korean patients initially diagnosed with idiopathic ventricular fibrillation.
Europace
November 2023
Division of Cardiology, Department of Internal Medicine, Korea University College of Medicine and Korea University Anam Hospital, 73, Goryeodae-ro, Seongbuk-gu, Seoul 02841, Republic of Korea.
Aims: Idiopathic ventricular fibrillation (IVF) is a disease in which the cause of ventricular fibrillation cannot be identified despite comprehensive clinical evaluation. This study aimed to investigate the clinical yield and implications of genetic testing for IVF.
Methods And Results: This study was based on the multi-centre inherited arrhythmia syndrome registry in South Korea from 2014 to 2017.
Clinical and Genetic Features of Korean Inherited Arrhythmia Probands.
Korean Circ J
October 2023
Division of Cardiology, Korea University College of Medicine and Korea University Medical Center, Seoul, Korea.
Background And Objectives: Inherited arrhythmia (IA) is a more common cause of sudden cardiac death in Asian population, but little is known about the genetic background of Asian IA probands. We aimed to investigate the clinical characteristics and analyze the genetic underpinnings of IA in a Korean cohort.
Methods: This study was conducted in a multicenter cohort of the Korean IA Registry from 2014 to 2017.
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